Ceyhun, GokhanErbay, Guven2024-11-072024-11-0720200026-47251827-1618https://doi.org/10.23736/S0026-4725.20.05149-Xhttps://hdl.handle.net/11480/15607BACKGROUND: The aim of this study was to investigate the association between left ventricular diastolic dysfunction (LVDD) and erectile dysfunction (ED) without overt cardiovascular disease. METHODS: A total of 80 patients with LVDD and without a history of coronary artery disease were compared with 80 age- and gender-matched healthy controls. The International Index of Erectile Function Questionnaire (IIEF-5) was used to diagnose and grade ED. LVDD and its relation with ED severity were assessed. RESULTS: The mean age, Body Mass Index, total testosterone, low- and high-density lipoprotein cholesterol, and triglyceride levels did not significantly differ between the LVDD and control groups (P>0.05). There was a negative correlation between the stage of LVDD and IIEF-5 score (r=-0.635, P<0.05). Additionally, the left atrial volume index, peak TR velocity and E/e' ratio were independent risk factors for lowering the IIEF-5 score. CONCLUSIONS: This study indicates that LVDD is significantly associated with ED. There were significant associations between the increased severity of ED and the presence of LVDD in middle-aged men.eninfo:eu-repo/semantics/closedAccessErectile dysfunctionLeft ventricular dysfunctionEchocardiographyArticle68429530110.23736/S0026-4725.20.05149-X321632422-s2.0-85085299832N/AWOS:000582383900006Q4