Kraiem, HAbdullah, MIAmri, H2024-11-072024-11-0720030040-4039https://doi.org/10.1016/S0040-4039(02)02589-3https://hdl.handle.net/11480/15412The ethyl alpha-bromomethyl-beta-(diethoxyphosphoryl)acrylic acid ester 9 has been prepared by addition of bromine to allylphosphonate 7 then dehydrobromination with DBU in acetonitrile. Reaction of allylic bromide 9 with primary amines in a bimolecular S(N)2'-type mechanism in methanol at low temperature, gives rise to the 2-[alkylamino(diethoxyphosphoryl)methyl]acrylic acid ethyl esters 6. (C) 2002 Elsevier Science Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessdimethyl alpha-(bromomethyl)fumarate2-[alkylamino(diethoxyphosphoryl)methyl]acrytic acid estersArticle44355355510.1016/S0040-4039(02)02589-32-s2.0-0037433981Q3WOS:000180321100032Q2