İlk, Sedef2024-11-072024-11-0720182148-127Xhttps://search.trdizin.gov.tr/tr/yayin/detay/328969https://hdl.handle.net/11480/13602Phenolic compounds which have many bioactivities such as antioxidant, antimicrobialand also inhibition of quorum sensing-regulated violacein pigment production propertiesare one of the plant secondary metabolites. The objective of this study was to determinethe antioxidant, antimicrobial activity and the inhibition of quorum sensing (QSI) activityby the phenolic extract obtained from strawberry fruits (Fragaria×ananassa cv.‘Rubygem’). The phenolic content of extract was determined as 3089 ?g GAE g fw -1 .The antioxidant activity determined through the ABTS + and FRAP method was 28.4 and26.2 mmol TE L -1 respectively. The phenolic extract was able to inhibit all the evaluatedbacteria by the disc diffusion assay in the range of 3.12–18.36 mm and could inhibit thequorum sensing phenomena in bacteria. The strawberry phenolic extract exhibited highantioxidant capacity, antimicrobial and anti-quorum sensing properties. To ourknowledge, this is the first report on the quorum sensing inhibition activity of strawberryfruit extract. The discovery of non-toxic novel compounds within antibacterial and QSIactivity could lead to the development of antimicrobial therapeutic agents that can bealternative and complementary treatments against antibiotic resistant bacterial pathogens.eninfo:eu-repo/semantics/openAccessBiyolojiMikrobiyolojiKimyaTıbbiBiyoteknoloji ve Uygulamalı MikrobiyolojiArticle61217891794328969