Natural Compounds Used as Therapies Targeting to Amyotrophic Lateral Sclerosis

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dc.authorid0000-0002-2790-2544
dc.authorid0000-0002-2790-2544
dc.contributor.authorNabavi, Seyed F.
dc.contributor.authorDaglia, Maria
dc.contributor.authorD'Antona, Giuseppe
dc.contributor.authorSobarzo-Sanchez, Eduardo
dc.contributor.authorTalas, Zeliha S.
dc.contributor.authorNabavi, Seyed M.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2015
dc.departmentNiğde ÖHÜ
dc.description.abstractAmyotrophic lateral sclerosis (ALS) is a neuromuscular disease that occurs throughout the world with no racial, ethnic or socioeconomic boundaries. Despite its high morbidity and mortality, there are limited medications available for ALS that may increase survival in patients with amyotrophic lateral sclerosis by approximately 2-3 months. Inasmuch as negative effects of riluzole on muscle atrophy and wasting, weakness, muscle spasticity, dysarthria, dysphagia, and overall patient quality of life and its different adverse effects, much attention has been paid to natural products and herbal medicines. Overall scientific reports indicate that natural products have beneficial effects on patients with ALS low side effects and multiple targets. In the present paper, we review the scientific reports on beneficial role of natural polyphenolic compounds in treatment of ALS.
dc.identifier.doi10.2174/1389201016666150118132224
dc.identifier.endpage218
dc.identifier.issn1389-2010
dc.identifier.issn1873-4316
dc.identifier.issue3
dc.identifier.pmid25601606
dc.identifier.scopus2-s2.0-84944890821
dc.identifier.scopusqualityQ2
dc.identifier.startpage211
dc.identifier.urihttps://dx.doi.org/10.2174/1389201016666150118132224
dc.identifier.urihttps://hdl.handle.net/11480/4065
dc.identifier.volume16
dc.identifier.wosWOS:000349390000003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherBENTHAM SCIENCE PUBL LTD
dc.relation.ispartofCURRENT PHARMACEUTICAL BIOTECHNOLOGY
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAmyotrophic lateral sclerosis
dc.subjectnatural substances
dc.subjectpolyphenol
dc.subjectoxidative stress
dc.titleNatural Compounds Used as Therapies Targeting to Amyotrophic Lateral Sclerosis
dc.typeArticle

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