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Öğe A new record for the flora of Turkey: Scorzonera ketzkhovelii Grossh. (Asteraceae)(TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2010) Hamzaoglu, Ergin; Aksoy, Ahmet; Martin, Esra; Pinar, Nur Muenevver; Colgecen, HaticeScorzonera ketzkhovelii Grossh. (Asteraceae) was recently collected from Yusufeli, Artvin (north-east Anatolia) and it has been reported as a new species record for the flora of Turkey. It is described and illustrated. In addition, its karyological features and pollen morphology are given.Öğe An investigation of oxidative stress and coenzyme Q10 levels in patients with head and neck squamous cell carcinomas(SPRINGER, 2019) Aksoy, Ahmet; Kurnaz, Senem CengelObjectiveThe purpose of this study was to determine the oxidative states of head and neck squamous cell carcinoma (HNSCC) patients by measuring their plasma levels of malondialdehyde (MDA), an indicator of lipid peroxidation, 3-nitrotyrosine (3-NT), an indicator of protein oxidation, and the coenzyme Q10 (CoQ10), an important antioxidant, and compare them with healthy individuals.Materials and methodsThe plasma MDA, 3-NT and CoQ10 levels of 35 patients and 20 healthy individuals were measured with the high-performance liquid chromatography (HPLC) method. By comparing the patients' smoking habits, stage of the disease, size of the primary tumor and the presence of lymph nodes and the values of healthy individuals, the oxidative stress load of HNSCC patients was determined.ResultsThe mean plasma MDA levels of carcinoma patients were two times higher than those of healthy individuals (p<0.001). When the mean plasma 3-NT levels of patients and healthy individuals were compared, no significant difference was found (p>0.05). The mean plasma CoQ10 level of patients was low when compared with healthy individuals; however, no significant difference was detected (p>0.05). In addition, as the stage and tumor size increased in HNSCC patients, their non-enzymatic antioxidant levels significantly decreased (p<0.05).ConclusionsIn HNSCC patients, lipo-oxidative damage increased while nitrosative stress did not change; however, antioxidant activity decreased which in turn increased both lipid peroxidation and oxidative stress. These findings support the contention that oxidative stress strongly reflects the health status of HNSCC patients.Öğe Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy(AVES, 2020) Ekinci, Adnan; Dağıstan, Hakan; Aksoy, Ahmet; Ekinci, HalilObjective: This study aimed to compare the serum oxidative stress levels of patients with adenotonsillar hypertrophy (ATH) with those of controls and to investigate the effects of adenotonsillectomy on the oxidative stress levels. Material and Methods: Thirty healthy children (mean age, 6 years) and 30 patients with ATH (mean age, 7 years) aged 2-12 years were included in the study. Serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and paraoxonase (PON) levels were compared between the patient and control groups. The preoperative and postoperative levels were also compared within the patient group. Results: The TOS and OSI levels were significantly higher in the patient group than in the control group (p=0.007 and p=0.027, respectively). There was no significant difference between the patient and control groups in terms of the TAS and PON levels (p=0.399 and p=0.237, respectively). The TOS and OSI levels in the patient group were significantly higher in the preoperative than in the postoperative period (p=0.005 and p=0.023, respectively), whereas there were no significant differences in the TAS and PON levels between the preoperative and postoperative period (p=0.192 and p=0.262, respectively). Conclusion: These findings demonstrate that patients with ATH are exposed to high levels of oxidative stress and that adenotonsillectomy normalizes the oxidative stress. © 2020, AVES. All rights reserved.Öğe Evaluation of the Nasal Olfactory Mucosal Area in Patients Affected by Olfactory Dysfunction Associated with Coronavirus Disease 2019(AVES, 2023) Aksoy, Ahmet; Çırakoğlu, Mehmet Furkan; Bingöl, Fatih; Bingöl, Buket ÖzelObjective: While researchers have posited various factors, the precise etiology of anosmia in coronavirus disease 2019 (COVID-19) patients remains elusive. We aimed to investigate the relationship between the status of the nasal olfactory mucosal area and medical and demographic variables in patients with COVID-19-related olfactory dysfunction. Methods: In a retrospective analysis, we scrutinized data from 65 adult COVID-19 patients who exhibited olfactory impairment, excluding those with specific medical histories or age-related criteria. Our assessment comprised the analysis of paranasal sinus computed tomography scans to assess inflammation within the nasal olfactory mucosa. Olfactory testing was not employed in this study. We conducted a comprehensive investigation to explore potential associations with gender, age, septal deviation status, taste disorders, and the timing of the onset of olfactory dysfunction. Results: The average age of the patients was 31.6 ± 12.4 years, with 18 (27.7%) male and 47 (72.3%) female patients. Of 65 patients, 43 (66.2%) reported olfactory dysfunction simultaneously with COVID-19, while 22 (33.8%) experi-enced it after testing positive. Taste abnormalities were present in 49 patients (75.4%). Thirty-seven patients (56.9%) had a nasal septum deviation. Inflammation in the olfactory mucosal region was found in 8 patients (12.3%). The study did not find any significant association between inflammation in the olfactory mucosa and factors like age, gender, taste disorders, or the type of olfactory dysfunction. Still, a significant correlation was found between inflammation in the olfactory mucosal region and nasal septal deviation (P = .009). Conclusion: In COVID-19 patients with olfactory dysfunction, nasal septal deviation was the most common accom-panying factor with olfactory mucosal area inflammation, suggesting it may be a potential risk factor. © Author(s).Öğe Isolated Cricoid Cartilage Fracture After Blunt Thoracocervical Trauma: A Case Report(Emergency Medicine Physicians Assoc Turkey, 2024) Aksoy, Ahmet; Guresci, KursatAlthough cricoid cartilage fracture is rare because of the firm and stable structure of the cricoid cartilage, it can cause fatal complications. Prompt diagnosis and rapid airway safety are incredibly vital. A 24-year-old male patient was admitted to the emergency department due to blunt trauma to the thoracocervical region. The computed tomography taken after the first interventions detected a displaced fracture of the cricoid cartilage. In light of the patient's clinical findings, the patient was treated conservatively and non-surgically with close follow-up of the airway safety.Öğe Orbital Abscess in the Case of Amblyopia(AVES, 2019) Aksoy, Ahmet; Güngör, Özge Özata; Zor, Kürşat RamazanThere are some orbital and intracranial complications of acute and chronic inflammation of paranasal sinuses. Some fatal complications can be encountered despite the wide use of antibiotics. Periorbital cellulitis occurs as a result of inflammation of ethmoid sinuses and is mostly seen in childhood. This clinical condition is characterized by swelling, redness, and ocular pain but the vision is unaffected. A 16-year-old boy with amblyopia on the left eyeball was admitted to our outpatient clinic with a complaint of a headache lasting for two days. Medical treatment was started with the diagnosis of acute sinusitis. In the second day of treatment, the patient was admitted to our clinic because of swelling, redness, and pain on the right eyeball and was hospitalized with the diagnosis of right periorbital cellulitis. Despite using two different intravenous antibiotics, the patient’s visual acuity was decreased and his eyeball move-ments’ limitation was increased within hours. The patient did not respond to treatment and therefore subperiosteal orbital abscess was drained surgically. It is important to consider the age and other conditions of a patient to decrease mortality and morbidity when treating a patient with swelling of the eyelids. Sinusitis is a common disease that may cause an orbital abscess, epidural abscess, and intracranial complications. © 2019 by Turkish Rhinologic Society.Öğe Sensory profiles, behavioral problems, and auditory findings in children with autism spectrum disorder(Taylor & Francis Ltd, 2023) Gundogdu, Ummugulsum; Aksoy, Ahmet; Eroglu, MehtapObjective: This study examined the relationship between sensory processing (SP) differences and behavioral problems in children with autism spectrum disorder (ASD). We also investigated whether audiological test results could objectively detect auditory processing differences.Method: Forty-six children with ASD, ages 3-9 years, were enrolled in the study. Problematic behaviors and sensory processing of children were assessed using scales. The otolaryngologist performed a detailed head and neck examination and a formal audiological examination was performed by an audiologist.Results: Stereotypy, hyperactivity, and irritability were related to sensation seeking. Stereotypy was also associated with visual processing. Touch processing differences was related to irritability and inappropriate speech. Lethargy was associated with auditory processing. There were no differences in SP and behavior problems in the children whose audiological profiles could be measured between those who passed or failed the test.Conclusion: There was an association between SP differences and behavioral problems in children with ASD, supporting previous studies. Audiological test results did not reveal the SP differences documented in the parent forms.Öğe Submucosal Foreign Body in Oropharynx(2019) Kurnaz, Senem Çengel; Aksoy, AhmetAlthough, in children, foreign body aspirations arefrequently seen, in adults they are rarely seen. Theaspirated foreign bodies usually settle into the noseand ear, also less frequently localization site is theoropharynx. A foreign body can cause symptoms suchas dysphagia, unilateral bloody nasal discharge andrespiratory disorders according to its localization.They sometimes require immediate treatment.Submucosal localizations of a foreign body is seenrarely. Although, aspirated foreign bodies aregenerally in small size, they can sometimes be rigid,traumatic and larger materials which are hard toaspire. In this article, the clinical condition of an adultmale patient, after consumption of honey, dependingon the submucosal settlement of a metal wirebelonging to honey comb, is presented.Oropharyngealforeign bodies are removed under local anesthesiawith endoscopic methods in outpatient clinicconditions; also they are extracted under generalanesthesia with direct laryngoscopy in difficult cases,like our patient.
