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    INVESTIGATION OF THE RELATIONSHIP BETWEEN FATIGUE, DEPRESSION AND NUTRITIONAL STATUS IN PATIENTS WITH RELAPSING REMITTING MULTIPLE SCLEROSIS
    (2024) İnbaşı, Elif Gökçe; Alim, Nural Erzurum; Yetkin, Mehmet Fatih
    This study aimed to evaluate the nutritional status, depression and fatigue status of patients with Relapsing Remitting Multiple Sclerosis (RRMS). The study was carried out on 30 MS patients (Patient Group: PG) and a control group consisting of 30 healthy volunteers with similar characteristics (Control Group: CG). It was found that the relationship between depression and fatigue among MS patients was positive (p<0.05). The mean score of the Fatigue Severity Scale (FSS) was 5.65±1.57 in PG patients and 3.10±0.97 in CG patients. The fatigue level of the patients was significantly higher than that of the controls (p<0.05). A negative correlation was found between vitamin B12 intake and the scores of the FSS and Beck Depression Inventory (BDI) in patients with PG (p<0.05). The study showed that fatigue and depression in MS patients were closely related their dietary habits. Since low serum B12 levels may increase the risk of fatigue and depression, attention should be paid to vitamin B12 intake. In order to improve the quality of life of MS patients, their nutrition should be closely monitored and a balanced and healthy nutrition plan appropriate to their needs should be implemented.

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