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    Is malignancy effective in the healing time of pressure ulcers in intensive care patients?
    (Bayrakol Medical Publisher, 2021) Argun, Guldeniz; Aydin, Murat; Incel, Gulyasar Ketenci; Karaismailoglu, Eda
    Aim: In this study, we aimed to investigate the duration of wound healing and an effective treatment management approach to patients with or without malignancy receiving wound care to provide effective wound care and to accelerate discharge. Material and Methods: Three hundred and forty-five patients who were treated in our clinic were included in the study. Records of patients with pressure ulcers among those who stayed in the Surgical Intensive Care Unit between January 1, 2018 and January 1, 2020 were accessed. Patients' pressure ulcers were graded on the Waterlow scale and standardized therapies were applied according to the grades. Dates of admission to the Intensive Care Unit (ICU), the pressure ulcers grades, comorbidities, laboratory values, administered treatment protocols and treatment response times were retrieved from the records and evaluated. Results: The patients were divided into two groups: patients with malignancy (Group M, n = 78) and those without malignancy (Group NM, n = 73). Comparison of all parameters according to pressure ulcer stages revealed a significantly low albumin level in malignant patients with Stage 2 and 3 pressure ulcers when compared to the non-malignant patients (Group M / Group NM, Stage 2 p<.01 and stage 3 p = 0.015). In malignant patients with low albumin levels and Stage 2 pressure ulcers, the wound healing time was prolonged statistically significant (Group M/Group NM, 13.28 +/- 5.64/11.50 +/- 6.34 days, p = 0.047). No significant difference was established in the mean duration of wound healing between patients with and without malignancy when groups were taken up in general (Group M/Group NM: 8.00 +/- 6.49 / 6.67 +/- 6.35 days, p = 0.52). Discussion: Malignancy does not play a role in the duration of wound healing in malignant and non-malignant patients treated in the intensive care unit at stage 1 pressure wounds. Furthermore, there is a difference in the duration of wound healing between malignant and non-malignant patients, even for Stage 2 and 3 pressure ulcers on the Waterlow scale.
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    Residual Symptoms After Carpal Tunnel Decompression and Treatment With Gabapentin: A Multicenter Study
    (Springernature, 2021) Aydin, Murat; Argun, Guldeniz; Acar, Baver; Arikan, Murat; Cinaroglu, Selim; Mert, Ahmet; Togral, Giiray
    Objectives To identify postoperative residual symptoms of carpal tunnel syndrome (CTS) and to investigate the effectiveness of gabapentin in the treatment of residual symptoms. Materials and methods Of a total of 412 patients who underwent surgery for CTS in four centers over a four-year period, 14 who had residual symptoms after CTS release and did not receive gabapentin (Group A) and 14 patients with postoperative residual symptoms and received gabapentin were included in this retrospective study. Postoperative residual symptoms were defined as persistent nocturnal numbness and tingling with or without occasional daytime pain. Tinel's and Phalen's tests were performed for the diagnosis of residual symptoms. Functional Severity Score (FSS), Symptom Severity Score (SSS), and Visual Analog Scale (VAS) were used to evaluate functional outcomes, severity of symptoms, and numbness and sleep quality, respectively at six and 12 weeks postoperatively. Results There was no statistically significant difference in the mean postoperative FSS (p=0.845) and VAS-numbness scores (p=0.367) between the groups. However, there was a statistically significant difference in the mean postoperative SSS (p=0.025) and VAS-sleep quality scores (p<0.001) between the groups. Conclusion Gabapentin treatment can be a treatment of choice for residual symptoms after CTS surgery and clinical improvement can be achieved owing to its relieving effect, particularly in nocturnal symptoms of patients having neuropathic pain.