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    ANTIOXIDANT ANTIMICROBIAL OXIDANT AND ELEMENTS CONTENTS OF XYLARIA POLYMORPHA AND X. HYPDXYLON (XYLARIACEAE)
    (Parlar Scientific Publications (P S P), 2021) Saridogan, Beste Gizem Ozbey; Islek, Cemil; Baba, Hayri; Akata, Ilgaz; Sevindik, Mustafa
    In the current study, antioxidant, oxidant, and antimicrobial potentials of Xylaria polymorpha (Pers.) Grey. and X hypoxylon (L.) Grey. were determined. Also, the levels of elements accumulated by these fungi were measured. The samples were extracted with ethanol in soxhlet apparatus. Antioxidant and oxidant potentials were determined using Rel Assay kits. Antimicrobial activities were tested using the agar dilution method. Element contents were determined using atomic absorption spectrophotometer. As a result of the studies, TAS, TOS, and OSI values of X hypoxylon were determined as 3.794 +/- 0.188, 8.609 +/- 0.171, and 0.228 +/- 0.015, respectively. TAS, TOS, and OSI values of X. polymorpha were determined as 5.390 +/- 0.176, 14.738 +/- 0.126, and 0.274 +/- 0.008, respectively. Besides, it was observed that the antimicrobial activities of the extracts of mushrooms were effective at 50-400 mu g/mL concentrations. Element contents were determined to be at normal levels compared to literature data. As a result, it was determined that X. polymorpha and X. hypoxylon have antioxidant and antimicrobial potentials.
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    Biological Activities of Wild Poisonous Mushroom Entoloma sinuatum (Bull.) P. Kumm (Boletales)
    (Kahramanmaras Sutcu Imam Univ Rektorlugu, 2022) Bal, Celal; Baba, Hayri; Akata, Ilgaz; Sevindik, Mustafa; Selamoglu, Zeliha; Akgul, Hasan
    In many studies conducted in recent years, it has been found that the beneficial natural ingredients found in mushrooms are very important in curing various diseases and eliminating disease factors. It has been reported that fungi that spread in different countries have biological activities. In this study, antioxidant level (TAS). oxidant level (TOS), and antibacterial and antifungalactivity of Entoloma sinuatum (Bull.) P. Kumm were determined. Ethanol extract of the mushroom was extracted in a Soxhlet apparatus. Antioxidant and oxidant levels were determined using Rel Assay TAS and TOS kits. Also. antimicrobial activity was tested against bacteria l and fungal strains using the agar dilution method. As a result of the studies. the TAS value of the mushroom was determined 2.64 +/- 0.15. the TOS value vas 6.58 +/- 0.23, and the OSI (Oxidative stress index) value was 0.25 +/- 0.02. In addition, it was determined that the ethanol extract of the mushroom was effective against bacteria at 200 and 400 mu g/mL, and against fungi at 50 mu g/mL concentrations. As a result, it was determined that E. sinuatum is a natural antioxidant and antimicrobial agent.