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Öğe Analysis of pupillary responses in pediatric patients with vitamin D deficiency(Springer, 2024) Bicer, Gamze Yildirim; Oztorun, Zeynep Yilmaz; Bicer, Kadir Eren; Zor, Kursad RamazanPurpose To evaluate the effects of vitamin D deficiency on pupillary responses in the pediatric population. Methods The study was conducted using data from the right eyes of 52 children with vitamin D deficiency and 52 healthy children. Measurements were taken under static and dynamic conditions with automatic pupillometry. Static measurements were performed at scotopic, mesopic, and photopic light intensities. The mean pupil dilation speed was calculated by observing the changes in pupil dilation over time according to dynamic measurements. Differences between patient and control groups were analyzed for the static and dynamic measurements and the mean pupil dilation speed. Results While the two groups were similar in terms of scotopic, mesopic, the first dynamic measurements, and the pupil dilation speed data (p > 0.05), a significant difference was found in the photopic conditions (p = 0.001). The mean pupil diameter of the patient group was 4.46 +/- 0.928 mm and 3.95 +/- 0.556 mm in the control group under photopic conditions. Conclusions Pediatric patients with vitamin D deficiency have significantly larger pupil diameters in photopic conditions than healthy children. These results suggest that there is an autonomic dysfunction in vitamin D deficiency in the pediatric population, especially pointing to the parasympathetic system.Öğe Can the long term using of pregabalin in fibromyalgia affect the choroid and retinal nerve fiber layer?(Springernature, 2022) Bicer, Gamze Yildirim; Zor, Kursad Ramazan; Bicer, Kadir Eren; Kucuk, Erkut; Kucuk, Esin BenliBackground In this study, the effects of long-term pregabalin use on the choroid and retinal nerve fiber layer were investigated in the fibromyalgia disease. Methods The patient group consisted of 41 fibromyalgia patients using pregabalin. The control group consisted of 41 newly diagnosed fibromyalgia patients who had not received any treatment yet. Choroidal and retinal nerve fiber layer thickness measurements were performed with Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA, USA) 30 minutes after pupil dilation with 1% tropicamide. Results There was no difference in subfoveal choroidal thickness, nasal choroidal thickness and temporal choroidal thickness between the patient and control groups (p > 0.05). Increasing the duration of drug use within the patient group was found to thin the retinal nerve fiber layer (p < 0.05). Conclusion We found that pregabalin had no effect on the choroid, while it had a thinning effect for retinal nerve fiber layer. It is recommended not to be preferred pregabalin in fibromyalgia patients with retinal nerve fiber layer damage such as diabetic retinopathy and glaucoma. Patients treated with pregabalin should have regular control in the ophthalmology clinic.Öğe Two major causes of morbidity in geriatrics: Cataract, knee osteoarthritis and patients' body awareness(Bayrakol Medical Publisher, 2023) Bicer, Kadir Eren; Bicer, Gamze YildirimAim: Cataract and osteoarthritis are important diseases that cause morbidity in the geriatric population. Age is an important risk factor for both diseases. There is no clear information about the correlation of the severity of diseases yet. Material and Methods: The cataract score for the right and left eyes and the osteoarthritis stage for the right and left knee of each patient were determined. After staging, body awareness questionnaire (BAQ) was administered to the patients to test their body awareness. In the study, the correlation of the patients' cataract scores and osteoarthritis stages was examined. In addition, relationships between the cataract score and the BAQ score and between the osteoarthritis stage and the BAQ score were analyzed. Results: There was a significant correlation between patients' cataract scores and osteoarthritis stages, but this correlation was not strong. Cataract progression was found to be more asymmetrical than osteoarthritis. It was also found that the relationship between the cataract stage and body awareness was much stronger than the osteoarthritis stage. Discussion:The diseases identified in this study have the potential to cause significant clinical and economic consequences when inadequately treated. Therefore, geriatric screening programs can provide a chance for treatment before diseases progress.