Yazar "Caglar B." seçeneğine göre listele

Listeleniyor 1 - 1 / 1
  • Küçük Resim Yok
    Öğe
    Evaluation of subclinical left ventricular systolic dysfunction using two-dimensional speckle- tracking echocardiography in patients with non- alcoholic cirrhosis
    (Hellenic Cardiological Society, 2014) Altekin R.E.; Caglar B.; Karakas M.S.; Ozel D.; Deger N.; Demir I.
    Introduction: Cirrhosis is associated with certain abnormalities in left ventricular (LV) structure and function. Two-dimensional speckle-tracking echocardiography (2D-STE) enables a rapid and accurate analysis of regional LV systolic mechanics in the longitudinal, radial and circumferential directions. The aim of this study was to precisely assess the differences among the 3 directions in the early impairment of LV myocardial contraction in non-alcoholic cirrhotic patients with preserved LV pump function.Method: A total of 75 subjects, including 38 cirrhotic patients and 37 healthy individuals, were enrolled. Using 2D-STE, the strain (S) and systolic strain rate (SRS) values belonging to the radial (R), circumferential (C), and longitudinal (L) functions of the LV were measured.Results: In the cirrhotic group, the LS(20.57 ± 2.1 vs. 28.7 ± 43.1, p<0.001) and LSR-S(1.1 ± 0.24 vs. 1.6 ± 0.3) values were found to be lower, whereas the CS(24.82 ± 2.57 vs. 19.16 ± 4.58, p<0.001) and C SRS(1.41 ± 0.3 vs. 1.2 ± 0.4, p±0.004) values were found to be higher than in the healthy control group. The RSand RSR-Svalues did not differ among the groups. A relationship was observed between the MELD score, which shows the severity of the disease, and the CS value (â: 0.211, p<0.01, 95%CI: 0.086-0.503).Conclusion: LV myocardial contraction was impaired in the longitudinal direction. However, LV pump function was augmented by the circumferential shortening during the ventricular systole. Using the 2D-STE method for the regional evaluation of the LV, the LV damage can be detected in the subclinical phase in cirrhotic patients. © 2014, Hellenic Cardiological Society. All rights reserved.