Yazar "Cihan, Ahmet" seçeneğine göre listele
Listeleniyor 1 - 11 / 11
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Changing Aspects of Male Sexual Functions Accompanying Treatment of Benign Prostatic Hyperplasia With Silodosin 8 mg Per Day(Elsevier Sci Ltd, 2020) Cihan, Ahmet; Kazaz, Ilike Onur; Yildirim, Omer; Deliktas, Hasan; Ongun, Sakir; Gul, Umit; Sahin, BahadirBackground: Alpha-adrenergic antagonist treatment for benign prostatic hyperplasia (BPH) and drug-related sexual side effects are frequent in aging men. Aim: To investigate functional changes in erectile and ejaculatory aspects of male sexuality under Silodosin 8 mg per day treatment for BPH. Methods: Sexually active patients diagnosed with BPH and who initiated Silodosin treatment were the subjects of the study. The International Prostate Symptom Score, premature ejaculation patient profile (PEP-male) questionnaire, Sexual Health Inventory for Men (SHIM) questionnaire, and estimated intravaginal ejaculation latency time (IELT) values of the participants were used to evaluate sexual functions. Data evaluation was performed in 8 urology clinics retrospectively. Outcomes: Participant ratings for SHIM, PEP, and estimated IELT were the primary outcome measures in the study. Results: Among 187 recruited patients, data of 98 patients, who completed the trial period in the study, were eligible. The median age of the eligible participants who completed the trial period for 3 months was 59.5 years (range 45-82). 16 patients of 187 (8%) reported a desire for drug withdrawal for anejaculation during the recruitment period. 46 (46.9%) and 49 (50%) patients reported anejaculation in the first and third month of the treatment, respectively. De novo erectile dysfunction was noticed in 15 patients (15.3%). There was a significant increase in the estimated IELT of subjects in both the first (P = .01) and third ( P = .002) month. SHIM-1 (P = .008), SHIM-total (P = .009), and PEP scores (P = .008) were also improved in the third month of the treatment. Neither baseline patient characteristics nor changes in the International Prostate Symptom Score after treatment predicted final outcomes with multivariable analysis. The subgroup analysis of participants who reported anejaculation also revealed better outcomes compared with participants ejaculating naturally in the third month as per SHIM ratings. Clinical Implications: Despite several male patients having dry orgasms due to Silodosin-induced anejaculation, the majority experienced improved erectile function. Strengths & Limitations: The present study demonstrated pioneering results while investigating both erectile and ejaculatory dimensions of the male sexual function during Silodosin treatment for BPH. However, lack of partner evaluation, low follow-up rates, and lack of knowledge about reasons why subjects are lost to follow-up after drug initiation have limited our interpretation. Conclusion: Most patients using Silodosin 8 mg per day for BPH treatment experienced improvement in their erectile function, estimated IELT, and premature ejaculation profile in the third month of the treatment. Underlying mechanisms and reasons for individual differences necessitate further investigation. Copyright (C) 2020, International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.Öğe Comparison of Efficacy and Complications of Holmium Laser and Pneumatic Lithotripters Used in the Ureterorenoscopic Treatment of Proximal Ureter Stones, a Multi-Center Study of Society of Urological Surgery Aegean Study Group(Galenos Yayincilik, 2018) Irer, Bora; Sen, Volkan; Erbatu, Oguzcan; Yildiz, Alperen; Ongun, Sakir; Cinar, Onder; Cihan, AhmetObjective:The aim of this study is to compare the efficacy and complications of holmium laser and pneumatic lithotripsy used in the ureterorenoscopic treatment of proximal ureteral stones. Materials and Methods: Data of 638 patients, who underwent ureterorenoscopy (URS) due to proximal ureteral stones in different centers, were obtained from patient files. The patients were divided into two groups according to the type of lithotripter used: group 1; laser lithotripter (n=324; 50.8%) and group 2; pneumatic lithotripter (n=314; 49.2%). URS was considered successful upon determination stone-free status with the imaging methods after treatment. The effectiveness and the complications of holmium:yttrium-aluminum-garnet laser and pneumatic lithotripsy were compared. Results: The total success rate of URS was 82.6% and the complication rate was 8.1%. The mean age of patients was similar between the groups; however, the body mass index values, stone surface area and stone Hounsfield unit were significantly higher in group 1. Although the mean operative time, complication rate and the mean length of hospital stay were similar between the groups; the URS success and postoperative ureteral J stent use rates were significantly higher in group 1 and the push-back rate was significantly higher in group 2. Conclusion: If laser lithotripsy is available in a clinic, we believe that it is better to use it as the first option in the treatment of proximal ureter stones. However, considering that it is not easy to access laser lithotripters due to their high cost in Turkey, pneumatic lithotripters may be an effective and inexpensive alternative that can also be safely used in these cases.Öğe Effects of androgen deprivation therapy on cognitive functions in patients with metastatic prostate cancer: A multicentric, prospective study of the Society of Urological Surgery Andrology group(Wiley-Hindawi, 2021) Cinar, Onder; Turunc, Tahsin; Kazaz, Ilke Onur; Yildirim, Omer; Deliktas, Hasan; Cihan, Ahmet; Gudeloglu, AhmetAims of the study The aim of this study was to investigate the impact of testosterone deficiency on cognitive functions in metastatic prostate cancer patients receiving androgen deprivation therapy (ADT). Methods In this multicentric prospective study, 65 metastatic prostate cancer patients were evaluated. Demographic and clinical data were recorded. Cognitive functions were assessed using the Symbol Digit Modalities Test, the California Verbal Learning Test Second Edition, the Brief Visuospatial Memory Test-Revised, and the Trail Making Test. Depressive symptoms were assessed using the Beck Depression Inventory. Cognitive functions and depressive symptoms were recorded before the androgen deprivation therapy and at the 3- and 6-month follow-ups. Results At the basal cognitive assessment, the mean Symbol Digit Modalities Test, the California Verbal Learning Test Second Edition, the Brief Visuospatial Memory Test-Revised scores were 25.84 +/- 17.54, 32.68 +/- 10.60, and 17.63 +/- 11.23, respectively, and the mean time for the Trail Making Test was 221.56 +/- 92.44 seconds, and were similar at the 3-month, and 6-month controls (P > .05). The mean pretreatment, third and sixth month testosterone levels were 381.40 +/- 157.53 ng/dL, 21.61 +/- 9.09 ng/dL and 12.25 +/- 6.45 ng/dL (P < .05), and the total PSA levels were 46.46 +/- 37.83 ng/mL, 1.41 +/- 3.31 ng/mL and 0.08 +/- 0.14 ng/mL (P < .05), respectively. Conclusion The ADT in patients with metastatic prostate cancer does not affect patients' cognitive functions and depressive symptoms. However, further prospective randomised studies with higher cohorts and longer follow-up periods are needed.Öğe Frequent witnessing to interparental conflict and low parental availability for leisure-time is associated with dysfunctional voiding in primary school children(Wiley, 2021) Cihan, Ahmet; Unalan, AdnanAim Aspects of parenting are an under-investigated topic amongst children with voiding complaints. We aimed to investigate the association between voiding complaints amongst children and two specific parenting-related behaviours: 1) parental availability during the child's leisure time and 2) frequency of witnessing interparental conflict. Material and Method Children aged between 6 and 11 years with their parents were the participants. Two survey forms and informed consent form were sent to potential participants via children's teacher. Voiding dysfunction complaints were evaluated with the Dysfunctional Voiding and Incontinence Symptom Scale (DVISS). Results Data analyses were performed with 1101 eligible participants. The mean duration of parental availability during the child's leisure time was below 2 hours per day. Nearly one out of every four children witnessed interparental conflict at least once a month. Age, educational level of the mother, parental availability for the child's leisure time, and frequency of witnessing parental conflicts were found to be significantly associated with DVISS ratings. Adjusting age, socioeconomic level, and educational level of the parents and later adjusting parental availability during the child's leisure time did not change the association of frequency of witnessing interparental conflict with DVISS rates. An increase in the age, educational level of the mother, and parental availability during the child's leisure time was correlated with better scores on DVISS, while an increase in the frequency of witnessing interparental conflict strongly correlated with worse scores. Conclusion Exposing children to interparental conflicts and shorter togetherness with their leisure time is associated with voiding complaints.Öğe Interrelation Between Appearance Anxiety and Sexual Functions in Women: The Role of Surgical Scars, Morphologic Features, and Accompanying Depression(Elsevier Sci Ltd, 2019) Cihan, Ahmet; Cihan, EsraIntroduction: The findings regarding the association between body mass index (BMI) and sexuality outcomes are mixed. Subjective body image has been found to be more salient in predicting sexual function than actual body size. Previous studies have demonstrated appearance anxiety to be particularly significant. Aim: To evaluate the association between appearance anxiety and female sexual functions. Specific aims included the evaluation of body morphologic measurements with indicators other than BMI and determining the predictive role of surgical scars for appearance anxiety and female sexual function. Methods: Sexually active women who had been in a stable heterosexual relationship for >= 6 months participated in this study. Demographic features, anthropometric measurements including BMI, skin-fold thickness (SFT) measurements from 3 regions of the body (triceps, scapula, and abdomen) and waist circumference (WC) were assessed. Finally, participants were asked to complete the Appearance Anxiety Inventory, Female Sexual Function Index, and Beck Depression Inventory. Multivariate path analyses and hierarchical multiple regression analyses were performed. Main Outcome Measures: The correlations of age, BMI, presence of surgical scars, and measurements of BMI, WC, and SFT as independent variables with Beck Depression Inventory, Appearance Anxiety Inventory, and Female Sexual Function Index scores were the main outcomes of the study. Results: The data of 329 women were analyzed. The median age of the participants was 33 (19-52) years. The mean BMI was 24.5 (SD 3.5) kg/m(2). The prevalence of female sexual dysfunction was 22.8%. Multivariate analyses revealed that increased appearance anxiety (-0.45), presence of surgical scars (-0.28), accompanying depression (-0.15), SFT abdomen measurement (-0.16), and age (-0.13) were significantly associated with sexual function. Appearance anxiety was found to be associated with accompanying depression (0.56), presence of surgical scar (0.38), and measurements of the WC (0.22), BMI (0.14), SFT-abdomen (0.12), and SFT-triceps (-0.31). Clinical Implications: Clinicians should take the strong relationship between appearance anxiety and female sexual function into consideration. Body morphologic evaluation should not be limited to BMI; surgical scars and WC and SFT measurements may play a considerable role. Strengths & Limitations: A major limitation of this study was the lack of personal distress evaluation in the participants. Conclusion: Sexual complaints in middle-aged women revealed the strongest correlation with appearance anxiety. Further longitudinal studies are needed to reveal its underlying factors and implications for sexuality. Copyright (C) 2019, International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.Öğe Perceived Stress and Accompanying Low Urine pH Are in Relation to Bladder Pain Syndrome(Galenos Yayincilik, 2021) Cihan, Ahmet; Cihan, Esra; Cakmak, BulentObjective: The clinical relevance of low urine pH and perceived stress levels in patients with bladder pain syndrome (BPS) has not yet been clarified. In this study, we hypothesised that urine pH and perceived stress levels may differ in patients with BPS and that they may be related to each other. Materials and Methods: A prospective case control study was conducted to test the hypothesis. Patients aged >18 years who were newly diagnosed with BPS were included in the patient group. The control group consisted of healthy volunteers aged >18 years. The 10-item Perceived Stress scale (PSS-10), spot urine pH measurements, Interstitial Cystitis Symptom index (ICSI), Interstitial Cystitis Problem index (ICPI), visual analogue scale for pain (VAS-Pain) and quality-of-life (QOL) scores were evaluated. Independent samples t-test and multivariate regression with path analysis were performed. Results: The study evaluated 84 patients with BPS and 86 healthy participants. The mean spot urine pH, PSS-10, ICSI, ICPI, VAS-Pain and QOL scores were different between the patient group and control group. Spot urine pH level (p=0.01, odds ratio (OR)=0.31) and PSS-10 scores (p=0.01, OR=1.1) remained significant predictors of BPS in the multivariate analysis. Lower urine pH and higher perceived stress levels were associated with worse ICSI, ICPI, VAS-Pain and QOL scores. Conclusion: Acidic urine pH and high perceived stress levels are associated with the presence of BPS. Perceived stress is independent from low urine pH, as they each relate to BPS symptoms in a bidirectional manner.Öğe Predictive Factors of Ureterorenoscopy Outcomes in Proximal Ureteral Stones: A Multicenter Study of Aegean Study Group of the Society of Urological Surgery(Karger, 2020) Sen, Volkan; Irer, Bora; Erbatu, Oguzcan; Yildiz, Alperen; Ongun, Sakir; Cinar, Onder; Cihan, AhmetIntroduction: We aimed to evaluate the predictive factors in a holistic manner for ureterorenoscopy (URS) outcomes in proximal ureteral stones by a multicenter study. Materials and Methods: The data of patients who underwent URS for proximal ureteral stones between the years 2015 and 2018 in eight centers were recorded retrospectively. Patients were divided into two groups according to URS success: Group 1 consisted of patients with successful URS, and Group 2 consisted of patients with unsuccessful URS. The two groups were compared in terms of risk factors, stone, and clinical characteristics of patients. Results: A total of 638 patients were included in the study. Group 1 consisted of 527 (82.6%) patients, and Group 2 consisted of 111 (17.4%) patients. In multivariate logistic analysis, the key risk factors for URS success was found to be age (OR = 0.980, 95% [CI] = 0.963-0.996, p = 0.018), stone area (OR = 0.993, 95% [CI] = 0.989-0.997, p = 0.002), and operation time (OR = 0.981, 95% [CI] = 0.968-0.994, p = 0.005). Conclusions: To make the treatment decision of proximal ureteral stones, it is necessary to examine several parameters including available equipment, stone, and patient characteristics. Physicians should keep these risk factors in mind in the decision of treatment options.Öğe Prevalence of Poor Sleep Quality and Its Determinants Among Men Suffering from Erectile Dysfunction(Galenos Publ House, 2023) Cihan, Ahmet; Kazaz, Ilke Onur; Duran, Mesut Berkan; Yildrim, Omer; Baser, Aykut; Guel, Uemit; Hasirci, ErayObjective: Recent findings implicate a higher prevalence of erectile dysfunction (ED) among men with sleep disorders. We investigated sleep quality among men with ED. Materials and Methods: A prospective study was conducted at 12 different andrology outpatient clinics among men with complaints of insufficient erections. The subjective quality of sleep was measured using the Pittsburgh Sleep Quality Inventory. Erectile function and its dimensions were measured using the International Index of Erectile Function (IIEF) questionnaire. The age-adjusted Charlson comorbidity index and Beck Depression Inventory were used to evaluate interrelations with comorbid disease severity and depression of the subjects consecutively in the study. Results: Among 431 eligible men, the median age of the participants and their erectile function scores in the IIEF were 51 [interquartile range (IQR)=43-59] and 16 (IQR=11-19), respectively. Poor sleep was observed in 192 of 431 (44.5%) subjects. Multivariable analysis revealed that younger age [odds ratio (OR)=0.95, p=0.01], lower body mass (OR=0.86, p=0.01), lower serum high-density lipoprotein cholesterol (OR=0.95, p=0.02), and higher severity of depression (0R=2.1, p=0.0001) were predictors of poor sleep quality among men with ED. Conclusion: Nearly half of the men with ED also suffer from poor sleep. Younger age, lean body mass, and severe depression were the main predictors of poor sleep quality among ED sufferers.Öğe Self-esteem and positive body image to overcome female sexual dysfunction(Acad Medicine Singapore, 2023) Cihan, Ahmet; Cihan, Esra[Abstract Not Available]Öğe Sequential Ureterocalicostomy for An Adult Patient with Bilateral Ureteropelvic Obstruction Complicated with Kidney Stones(Galenos Publ House, 2024) Cihan, AhmetUreterocalicostomy is generally known as a salvage procedure performed for indications of ureteropelvic junction stricture recurrence and/or upper ureteric injury that precludes dependent ureteropelvic anastomosis. Here we report a patient with bilateral ureteropelvic junction obstruction and an intrarenal pelvis anomaly complicated with pelvic and lower calyceal kidney stones treated with bilateral sequential ureterocalicostomy with successful outcomes at the 1-year follow-up.Öğe The impact of hyperthyroidism on sexual functions in men and women: a systematic review and meta-analysis(Springernature, 2024) Cihan, Ahmet; Esen, Ahmet AdilThis study aimed to review the current knowledge on sexual dysfunction in men and women with hyperthyroidism through a systematic review and meta-analysis. Available clinical trials from the MEDLINE database were searched using a prerecorded protocol (Protocol Prospero ID: CRD42022340587), and obtained data were analyzed and reported according to the PRISMA guidelines. Pooled effect estimates were computed using a random-effects model. Twenty eligible studies were identified, of which 15 were included in this meta-analysis. The prevalence of erectile dysfunction was significantly higher in participants with hyperthyroidism than that in controls [odds ratio = 9.16 (95% confidence interval [CI], 5.0-16.5)]. Treatment of hyperthyroidism alone improved erectile functions [effect size, ES = 0.36 (95% CI, -0.01-72)] and mean intra-vaginal ejaculation latency time [ES = 0.63 (95% CI, 0.27-98)] among men with erectile dysfunction and/or premature ejaculation. The prevalence of premature ejaculation also decreased with treatment of hyperthyroidism [odds ratio = 0.11 (95% CI, 0.04-28). Women with hyperthyroidism demonstrated higher odds in female sexual dysfunction than controls [odds ratio = 4.34 (95% CI, 2.63-7.18)]. Female sexual function index scores in women with hyperthyroidism were also significantly lower than those in the controls with moderate effect sizes. An evident and reversible disruption of sexual functions under hyperthyroidism conditions was observed in both sexes.
