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Öğe A Rare Tumor Case in an Adult Patient with Neurofibromatosis: Lumbar Ependymoma(Wolters Kluwer Medknow Publications, 2022) Yakar, H.; Ertugrul, B.; Kaplan, M.In patients with type 1 neurofibromatosis (NF1), there is an increased susceptibility to tumor development in the central nervous system due to the loss of neurofibromin, an inactivator of the protooncogene Ras. NF1 has a broad clinical spectrum,which includes spinal tumors. Although the most common intramedullary tumor of the spinal cord in adults is ependymoma, few patients with NF1 accompanied by spinal ependymoma have been reported to date, and the localization of the tumors is cervical and thoracic in these cases. In this study, we report the case of a patient with NF1 presenting to our clinic with low back pain and gait disturbance. The patient had an intradural extramedullary ependymoma at the L2-3 vertebra level. This report is the first case of NF1 with spinal ependymoma localized in the lumbar region.Öğe Potential Nutritive Value of Honey Locust (Gleditsia triacanthos) Pods from Different Growing Sites for Ruminants(TARBIAT MODARES UNIV, 2012) Kamalak, A.; Guven, I.; Kaplan, M.; Boga, M.; Atalay, A. I.; Ozkan, C. O.The nutritive values of honey locust pods obtained from different growing sites were evaluated by chemical composition and in vitro gas production techniques. Growing site was found to have a significant (P< 0.001) effect on the chemical composition. The CP contents of honey locust pods ranged from 67.2 to 119.9 g kg(-1) DM. Water soluble carbohydrate (WSC) ranged from 122.3 to 152.2 g kg(-1) DM. Neutral detergent fibre (NDF) and acid detergent fibre (ADF) contents varied with growing site in the range of 299.6 to 414.3 and 195.3 to 262.9 g kg-1 DM, respectively. Condensed tannin (CT) contents ranged from 27.8 to 148.2 g kg(-1) DM. Polyethylene glycol (PEG) addition significantly (P< 0.001) increased gas production and some estimated parameters of honey locust pods obtained from different growing sites. However, honey locust pods obtained from different growing sites showed variable responses to PEG treatment. There were also significant (P< 0.001) differences among growing sites in terms of gas production and estimated parameters. Organic matter digestibility (OMD) and metabolizable energy (ME) contents of honey locust pods obtained from different growing sites without PEG supplementation ranged from 58.81 to 65.86% and 8.85 to 9.92 MJ kg(-1) DM respectively. The improvement in gas production, the OMD and ME with PEG emphasized the negative effect of tannins on digestibility. The increase (%) in the estimated OMD and ME contents ranged from 6.30 to 15.81% and 5.61 to 14.94%, respectively.