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Öğe Clinical Presentations and Surgical Outcomes in Traumatic Iris and Lens-Related Injuries Due to Blunt Trauma(Lippincott Williams & Wilkins, 2024) Ozer, Omer; Guclu, Emin S.Purpose:The aim of this study was to evaluate the clinical presentation, treatment options, and surgical outcomes of patients admitted with traumatic iris and lens-related injuries due to blunt trauma.Methods:This retrospective study included 43 eyes of 43 patients who presented with traumatic iris and lens injuries between September 01, 2022 and July 01, 2023.Results:The mean age was 46.1 +/- 14.6 years and the mean ocular trauma score was 74.7 +/- 9.9. According to the cause of injury, the most common cause in males is assault, and the most common cause in females is fall. Nine (20.9%) patients underwent pars plana vitrectomy. Six (14%) patients underwent cataract surgery with phacoemulsification and intraocular lens implantation into the bag.Conclusions:In conclusion, other concomitant pathologies may make these surgeries difficult to perform. Early evaluation and timely management are essential to achieve the best possible outcomes in patients with traumatic iris and lens-related injuries.Öğe Comparison of anatomical and functional outcomes of pars plana vitrectomy for rhegmatogenous retinal detachment with phaco-vitrectomy(Gazi Eye Foundation, 2024) Tanriverdi, Abdulbaki; Ozer, Omer; Eroz, Pinar; Dinc, Erdem; Dursun, Ozer; Adiguzel, UfukPurpose: The aim of the present study was to compare the anatomical and functional outcomes in patients who underwent pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RD) with those who underwent cataract surgery combined with PPV. Materials and Methods: A total of 159 eyes of 159 patients who presented to our outpatient clinic with the complaint of vision loss and underwent surgery with the diagnosis of rhegmatogenous RD were included in this study. Patients who underwent 23 gauge PPV combined with standard cataract surgery were included in group 1 (n=62) and patients who underwent 23 gauge PPV alone were included in group 2 (n=97). Demographic data, preoperative and postoperative best corrected visual acuity (BCVA), anatomical success rates, optical coherence tomography findings and complications were recorded. Results: The median BCVA value before surgery was 0.003 in group 1 and 0.016 in group 2 and the difference was not significant (p=0.69). After surgery, the median visual acuity value in both groups was 0.3 and the increase was significant in both groups (p<0.001 for both groups). Similarly, the postoperative manifest spherical equivalents were similar between the two groups and there was no statistically significant difference (p=0.92). Reoperation was required in 4 patients (6.5%) in group 1 and 15 patients (15.5%) in group 2 due to recurrent detachment and there was no significant difference between the two groups in terms of reoperation rates (p=0.087). Conclusion: Combined surgery in the treatment of rhegmatogenous RD can be safely performed without serious complications. © 2024 The author(s).Öğe Comparison of the Cosmetic Efficacy of Extractum Cepae and Silicone-Based Gel in Upper Blepharoplasty(Lippincott Williams & Wilkins, 2024) Guclu, Emin Serbulent; Ozer, Omer; Celik, Seda; Eroz, Pinar; Baysal, ZekiBackground:Upper eyelid blepharoplasty is one of the most common surgeries performed worldwide. However, an important problem after surgery is scar formation. The authors aimed to compare the efficacy of extractum cepae and silicone-based gels on postoperative scar appearance in patients undergoing upper eyelid blepharoplasty.Methods:After suture removal, patients were divided into 3 groups: group 1 [n=82, extractum cepae, sodium heparin, and allantoin mixture, Contractubex Gel (Merz Pharmaceuticals, Frankfurt, Germany)], group 2 [n=81, silicone-based gel (Dermatix Ultra Silicone Gel, Menarini, Singapore)], and group 3 (n=77, no additional treatment). Patients used the topical gels twice daily. All evaluations were performed on color photographs by 2 physicians during the postoperative first and third months.Results:The mean visual analog scale scores were significantly higher in all 3 groups in the postoperative first month (4.39 +/- 2.03, 4.41 +/- 2.57, and 4.33 +/- 2.46, respectively) compared with the postoperative third month (2.22 +/- 1.24, 2.15 +/- 1.38, and 2.29 +/- 1.47, respectively) (P=0.014, 0.037, and 0.026, respectively). The Is the scar more stiff score was higher in the postoperative first month compared with the third month.Conclusions:In conclusion, blepharoplasty scars improved up to the postoperative third month, but the topical gels used did not significantly improve the cosmetic appearance of blepharoplasty scars compared with the control group.Öğe Comparison of the effects of 0.05% topical cyclosporine A versus 0.1% topical cyclosporine A on recurrence and clinical parameters following pterygium surgery(Tubitak Scientific & Technological Research Council Turkey, 2024) Guclu, Emin Serbulent; Metin, Tamer; Ozer, Omer; Bektas, Fatma MerveBackground/aim: To compare the efficacy of topical 0.05% cyclosporine A (CsA) and 0.1% topical cyclosporine A (CsA) over a 6-month period following pterygium surgery, specifically evaluating their effects on postoperative recurrence and clinical parameters. Material and methods: This clinical study enrolled 245 patients with pterygium who underwent surgery using the conjunctival autograft technique with mitomycin C (MMC) were enrolled. Participants were divided into three groups: Group 1 (0.05% CsA) (n = 80), Group 2 (0.1% CsA) (n = 80), and a control group (n = 85). They were examined at postoperative first day, first week, first month and sixth month. The examination included best corrected visual acuity (BCVA), intraocular pressure (IOP), presence of inflammation, and ptergium recurrence, all of which were compared across the groups. Results: The mean age of the patients was 63.22 +/- 9.39 years, with 53.3% male and 46.7% female. The three groups were similar in terms of demographic characteristics and pterygium size. Inflammation in surgical area significantly regressed in all groups at 6 months postoperatively (p < 0.05). Inflammation in the first and sixth months was not different between the groups (p = 0.118, p = 0.580, and p = 0.435, respectively). The recurrence rate was not different between groups (p = 0.890). There was no statistically significant difference between groups regarding IOP (p = 0.818). A significant increase in BCVA after surgery was observed in three groups compared to preoperative levels (p < 0.05). Conclusion: This study showed that there was no difference between the efficacy of 6 month topical 0.05% CsA and 0.1% CsA application after pterygium surgery with the conjunctival autograft technique with MMC on postoperative outcomes. Including postoperative recurrence, IOP changes, BCVA changes and surgical area inflammation.Öğe Evaluation of peripheral blood inflammatory biomarkers in sickle cell disease with and without retinopathy(Springer, 2024) Ozer, Omer; Dogan, Levent; Baysal, Zeki; Basir, Hakan; Ciftci, Ali Turker; Eroz, Pinar; Guclu, Emin SerbuelentBackground The aim of this study was to evaluate the clinical significance of blood-cell associated inflammation markers in patients with sickle cell disease (SCD) and sickle cell retinopathy (SCR). Methods Neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte to lymphocyte ratio (MLR), systemic immune inflammation index (SIII), systemic inflammation response index (SIRI), systemic inflammation modulation index (SIMI) and aggregate systemic inflammation index (AISI) were calculated. This study included 45 healthy controls (Group 1) and 100 SCD (Group 2). Patients in Group 2 were then divided into two groups: without SCR (Group 3) and with SCR (Group 4), and patients with SCR (Group 4) were further divided into two groups: non-proliferative sickle cell retinopathy (NPSCR) (Group 5) and proliferative sickle cell retinopathy (PSCR) (Group 6). Results The mean values for NLR, PLR, SIII, SIRI, AISI, and SIMI were significantly higher in Group 2 compared to Group 1 (p = 0.011 for NLR, p = 0.004 for SIII, and p < 0.001 for others). Furthermore, AISI and SIMI parameters demonstrated statistically significant discriminatory power to distinguish Group 5 from Group 6 (p = 0.0016 and p = 0.0006, respectively). Conclusion Given the critical role of inflammatory mechanisms in the pathogenesis of SCD and its related complications, the assessment of blood-cell-associated inflammatory markers may present a pragmatic and advantageous approach to the clinical oversight and therapeutic intervention of SCD.Öğe Pediatric Canalicular Lacerations: Epidemiology and Surgical Outcomes(Lippincott Williams & Wilkins, 2024) Guclu, Emin S.; Ozer, OmerBackground:The aim of this study was to report the epidemiology and surgical outcomes of canalicular lacerations in the pediatric age group.Methods:All pediatric patients who underwent repair of canalicular lacerations of any cause were included in this study. Age, sex, mechanism of trauma, and type of stent used were recorded.Results:The study group consisted of 47 patients with a median age of 6.4 years (22 mo-17 y). Thirty of the patients were male (63.8%). The lower canaliculus was affected in 76.6% (n=36), the upper canaliculus in 40.4% (n=19), and both canaliculi in 17% (n=8). The most common cause of canalicular laceration was sharp objects (n=33, 70.2%).Conclusion:Canalicular laceration most commonly affects boys and especially involves the lower canaliculus. There was no difference in functional success between monocanalicular and bicanalicular stents. Prevention of canalicular lacerations should be the main focus.Öğe The effect of adrenaline and trypan blue used during cataract surgery on anatomical and functional outcomes in pseudoexfoliation syndrome patients(Taylor & Francis Ltd, 2024) Ozer, Omer; Dogan, Levent; Baysal, ZekiPurposeTo evaluate the effect of the intracameral adrenaline and trypan blue used during cataract surgery on corneal endothelial parameters in pseudoexfoliation syndrome (PEX) patients.MethodsThe patients were divided into four groups according to intraoperative use of agents during cataract surgery: intracameral adrenaline (1/10,000, 0.1 ml) (group 1), trypan blue (0.6 mg/ml, 0.1 ml) (group 2), combination of adrenaline and trypan blue (group 3) and none (group 4).ResultsPreoperative ECD, CV, HEX and CCT parameters were similar between the groups. A mean loss of 12.7% in ECD was observed at the postoperative third months compared to the preoperative. In group 3, ECD was found to be lower in the postoperative third months compared to the preoperative (p = 0.014). In the other groups, no statistically significant difference was found in preoperative and postoperative comparisons.ConclusionIn conclusion, the utilization of intracameral adrenaline or trypan blue did not cause a significant difference in corneal endothelium in PEX patients. However, their combined use may have a negative effect on endothelial cell density. In a cataract surgery performed in the presence of PEX, the increased likelihood of endothelial damage should be taken into consideration, and appropriate precautions should be taken preoperatively and intraoperatively.Öğe The effect of subretinal recombinant tissue plasminogen activator application for submacular hemorrhage(Gazi Eye Foundation, 2024) Ozer, Omer; Dinc, Erdem; Dursun, Ozer; Yilmaz, Emre Can; Turkmen, Ismail; Eroz, PinarPurpose: The aim of the present study was to evaluate the outcomes of subretinal tissue plasminogen activator (r-tPA) injection with pars plana vitrectomy (PPV) in patients with submacular hemorrhage (SMH) extending towards the fovea. Materials and Methods: The study included 10 eyes of 10 patients who underwent subretinal r-tPA injection with 23 G PPV due to SMH extending towards the fovea. Following standard 23 G PPV, r-tPA (Actilyse, 10 mg/mL, Boehringer-Ingelheim, Germany) at a concentration of 25 µg/0.1 ml was injected into the subretinal space with a 41 G needle at a concentration of 0.2-0.3 ml. Subsequently, fluid-air-12% C3F8 exchange was performed and intravitreal 1.25 mg bevacizumab was administered. After surgery, the patient was given appropriate head position according to the bleeding site. Results: The mean age of the patients was 73.9 ± 4.7 years, 4 (40%) were male and 6 (60%) were female. Two patients (20%) developed SMH due to retinal macroaneurysm rupture, while choroidal neovascular membrane was the cause of hemorrhage in 8 patients (80%). Best corrected visual acuity was 2.53 ± 0.49 logMAR preoperatively, 1.28 ± 0.66 at one month, 1.08 ± 0.64 at three months and 1.04 ± 0.62 at six months postoperatively and the difference was significant (p<0.001 for each parameter). Conclusions: In patients with submacular hemorrhage, r-tPA administered subretinally provides significant visual acuity improvement without serious complications. Copyright © 2024 The author(s).
