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    Analysis of pupillary responses in pediatric patients with vitamin D deficiency
    (Springer, 2024) Bicer, Gamze Yildirim; Oztorun, Zeynep Yilmaz; Bicer, Kadir Eren; Zor, Kursad Ramazan
    Purpose To evaluate the effects of vitamin D deficiency on pupillary responses in the pediatric population. Methods The study was conducted using data from the right eyes of 52 children with vitamin D deficiency and 52 healthy children. Measurements were taken under static and dynamic conditions with automatic pupillometry. Static measurements were performed at scotopic, mesopic, and photopic light intensities. The mean pupil dilation speed was calculated by observing the changes in pupil dilation over time according to dynamic measurements. Differences between patient and control groups were analyzed for the static and dynamic measurements and the mean pupil dilation speed. Results While the two groups were similar in terms of scotopic, mesopic, the first dynamic measurements, and the pupil dilation speed data (p > 0.05), a significant difference was found in the photopic conditions (p = 0.001). The mean pupil diameter of the patient group was 4.46 +/- 0.928 mm and 3.95 +/- 0.556 mm in the control group under photopic conditions. Conclusions Pediatric patients with vitamin D deficiency have significantly larger pupil diameters in photopic conditions than healthy children. These results suggest that there is an autonomic dysfunction in vitamin D deficiency in the pediatric population, especially pointing to the parasympathetic system.
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    Evaluating the Social Anxiety Depression Levels and Accompanying Psychosocial Problems in Children Diagnosed with Enuresis
    (Springernature, 2022) Oztorun, Zeynep Yilmaz; Beser, Nalan Gordeles; Oztorun, Kenan; Arabaci, Leyla Baysan
    Introduction: This study was conducted to evaluate the accompanying psychosocial problems in enuresis as well as the social anxiety-depression levels in children diagnosed with enuresis. Methods: This descriptive study investigating depression and social anxiety levels of children diagnosed with enuresis was carried out with 167 children who were followed up for at least six months following their enuresis diagnosis. All participating children had no other physical or mental illnesses and were aged five years or older. Data were collected using three measurement tools and evaluated using descriptive. correlational analyzes. Results: In this study, 69.4% of the children diagnosed with enuresis were aged 7-12 years. 38.3% of their parents used reward, while 37.1% preferred punishment as a method for toilet training their children. The children's depression and social anxiety mean scores were 21.48 +/- 7.29 and 54.58 +/- 8.84, respectively. A strong positive correlation was found between the children's mean depression and social anxiety scores (r=0.677, p<0.001). The median depression scores of children were found to be statistically significantly different according to the children's type of family, night sleep characteristics, type of enuresis, school success, and family life (p<0.05). Those with fragmented families (p=0.049). who did not sleep deeply at night (p=0.031), who slept for about 5-7 hours a day (p<0.01), and those whose school success was negatively affected by enuresis (p=0.021) and those who were exposed to negative family life (p=0.034) all obtained statistically significantly higher median depression scores. Conclusion: Children with enuresis had low depression and moderate social anxiety and their depression increased as their social anxiety increased. The children experienced psychosocial difficulties due to enuresis. When treating children with enuresis, it is necessary to consider both the affected child and their families through the adoption of a holistic approach, and also to evaluate the children both physically and psychosocially.
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    Evaluation of Haematological Parameters and Uric Acid in the Diagnosis of Late Onset Neonatal Sepsis
    (Springernature, 2023) Oztorun, Zeynep Yilmaz
    IntroductionA number of parameters studied in a whole blood count can be helpful in the diagnosis of neonatal sepsis. The platelet/lymphocyte ratio (PLR) is a systemic inflammatory marker in early sepsis and has been used as a diagnostic indicator in cardiovascular events and cancer. Being one of the major antioxidants in human biological fluids, serum uric acid is responsible for neutralising free radicals. The red cell distribution width/platelet ratio (RPR) is a diagnostic marker in adult inflammatory diseases. The objective of our study is to investigate the relationship of late neonatal sepsis with whole blood count parameters and serum uric acid levels.Materials and methodsNewborns older than postnatal three days who had clinical and laboratory findings of sepsis were included in the study. The study included 140 newborns who were divided into three groups, 53 in the culture-proven late sepsis group, 47 in the clinical sepsis group, and 40 in the healthy control group. The whole blood count parameters and serum uric acid levels were examined in both the clinical sepsis and proven sepsis patients at the time when they were diagnosed with sepsis.ResultsThe birth week was significantly lower in the evidenced and clinical sepsis patients compared to the healthy control group. Development of late sepsis was significantly higher in the male gender than in healthy controls. Serum uric acid levels were significantly higher in proven or clinical sepsis than in healthy controls. The level of serum uric acid (3.77 & PLUSMN;1.6) in proven sepsis was significantly higher than the control group (2.83 & PLUSMN;1.1). The uric acid level had an area under the curve (AUC) 0.552-0.717, 35% sensitivity, 95% specificity, 94.6% positive predictive value (PPV), and 36.9% negative predictive value (NPV) in the diagnosis of proven and clinical late sepsis. Neutrophil/lymphocyte ratio (NLR) was significantly higher in proven sepsis than in healthy newborns and was higher in the clinical sepsis group than in the proven sepsis group (p: 0.002). While the mean eosinophil value was 618.5 & PLUSMN;472.1 in proven sepsis, it was 549.3 & PLUSMN;294.9 in the control group and there was a statistically significant difference between the two groups (p: 0.036).ConclusionIn late-onset neonatal sepsis, the NLR level was higher, and the eosinophil level was lower in the clinical sepsis patients than in healthy newborns. We believe that a higher level of serum uric acid in sepsis is effective in the early diagnosis of patients who also had other clinical findings of sepsis.
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    Field study for determining the effect of COVID-19 on healthcare workers Effect of COVID-19 on healthcare workers
    (Bayrakol Medical Publisher, 2021) Cinaroglu, Nesibe Sultan; Oztorun, Kenan; Kacmaz, Mustafa; Oztorun, Zeynep Yilmaz
    Aim: This study determines the anxiety levels of health workers by evaluating their anxiety status in the challenging process of the pandemic. Material and Methods: One hundred forty health workers who studied at pandemic hospital were included in the study. The data were collected using the Pandemic Period Data Form (PPDF), and the State-Trait Anxiety Inventory (STAI), prepared for assessing anxiety levels of health workers in the face of the COVID-19 outbreak. Results: In the study there was a significant difference between the health care workers working in intensive care units and those working in non-intensive care units in terms of age, gender, and presence of children. We found that there was a significant difference in STAI state anxiety scores (p <.05) of health workers in terms of having children, and they had higher levels of state anxiety. On average, the health workers from intensive care units had higher levels of PPDF anxiety. In this study, we detected that the COVID-19 anxiety levels of the health workers between the ages of 20 and 30 were higher compared with those aged 41 and above (p < .05). Discussion: It was found that the pandemic process had a negative impact on health workers as their anxiety increased in this process. Elimination of the gaps related to application or information in the published guidelines can help health workers feel more safe.
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    Parents' knowledge and attitudes about adenovirus enteritis of children Parents' knowledge about adenovirus in children
    (Bayrakol Medical Publisher, 2021) Oztorun, Zeynep Yilmaz
    Aim: This study aimed to examine the effect of the sociodemographic characteristics of the parents of children hospitalized for adenovirus enteritis and child care attitudes of parents on the course of adenovirus enteritis. Material and Methods: A total of 57 patients aged <6 years who were hospitalized for adenovirus enteritis were included in the study. A questionnaire was administered to the parents to gather data on the patients' birth history, chronic diseases, and breastfeeding times, and parents' level of education and knowledge about adenovirus enteritis and dehydration. The questionnaire also included items about hygiene measures for dehydration. Kidney function tests, electrolyte values, and blood gas analysis were performed to evaluate the dehydration status of the patients objectively. Results: Of 57 patients, their mean age was 19.84 +/- 14.97 months. The mean number of patients' siblings was 1.76 +/- 0.76. 10.5% of parents had knowledge about adenovirus-related diarrhea. Parents believed that adenoviruses were transmitted through contaminated water (45.6%), food (17.5%), and surface (19.3%) and through human-to-human contact (17.5%). A significant relationship was found between parental education level and knowledge of diarrhea caused by an adenovirus (p = 0.032). In addition, a significant relationship was noted between parental education level and hand washing after each diaper change (p = 0.016). Moreover, no significant difference was found between the duration of breastfeeding and the time to initiation of oral intake after diarrhea (p = 0.501). Discussion: It was thought that having a large family, education level, working status of parents were factors that influence the course of adenovirus and the development of dehydration that would require hospitalization. We believe that families' knowledge of adenovirus infection and possible complications will help in preventing irreversible morbidities. Therefore, adenovirus infections need to be included in informative speeches in the field of preventive medicine.