DSpace Arşivi :: by Yazar "Ulusoy C." değerine göre listeleniyor

Listeleniyor 1 - 1 / 1

The efficacy of autologous serum eye drops for severe dry eye syndrome: A randomized double-blind crossover study
(Springer Verlag, 2014) Celebi A.R.C.; Ulusoy C.; Mirza G.E.
Background: To evaluate the efficacy of autologous serum (AS) eye drops for the symptomatic relief of severe dry eye syndrome (DES), as compared to conventional preservative-free artificial tears (PFAT). Methods: This prospective double-blind randomized crossover study used the Ocular Surface Disease Index (OSDI), tear film break-up time (TBUT), Schirmer's Test, and OXFORD Scale at baseline and after each of two 1-month treatment periods to measure the effect of 20 % diluted AS eye drops vs. PFAT in 20 consecutive severe DES patients that were refractory to conventional treatment. Results: The study included 20 (18 female and two male) severe DES patients (40 eyes). Significantly higher TBUT (P??0.05 [Mann-Whitney U test]). Conclusions: AS eye drops were more effective than conventional eye drops for improving tear film stability and subjective comfort in patients with severe DES. © 2014 Springer-Verlag Berlin Heidelberg.