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Öğe Synthesis and antimicrobial activities of novel bisacridine-1,8-dione derivatives(SPRINGER BIRKHAUSER, 2011) Kaya, Muharrem; Yildirir, Yilmaz; Celik, Gokcen Y.A series of bisacridine-1,8-dione derivatives were synthesized by one-pot reaction of aromatic dialdehydes, dimedone or cyclohexane-1,3-dione and primer aromatic amines in acetonitrile to utilizing Amberlyst-15 as a heterogeneous catalyst. The structures of compounds were characterized by FT-IR, NMR, and elemental analysis. Antimicrobial activities of these compounds were determined by using the disc diffusion method against to these gram-positive and gram-negative bacteria and yeast. The results were compared with reference discs.
