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    Nutritional status and calcium levels in serum and urine of primary hypertensives and normotensives
    (ASIAN JOURNAL OF CHEMISTRY, 2008) Kayakirilmaz, Kadriye; Bayol, Emel; Yilmaz, Hatice Bal; Ozgun, Hacer Kutluk; Ozbek, Tulay; Topuz, Dervis; Battaloglu, Rifat
    This research has been designed for the determination of the nutritional status, serum and urinary calcium (UCa) levels and correlation between UCa and blood pressure (BP). 31 Volunteers' patients with essential hypertension (HT) and 31 age- and gender-matched normotensive (NT) control subjects living in Ankara and Nigde from Turkey have participated in this study. 62 Subjects' 24 h urinary samples were collected. Besides, for determination of the correlation between 24 h UCa and overnight UCa (12 h UCa), 38 urine samples (9 patients and 29 control subjects) were collected. Nutritional status was evaluated according to their food consumption and physical examination. After analyzing the collected blood and urinary samples, the mineral status was also evaluated. Urinary and serum Ca levels were determined by flame atomic adsorption spectroscopy. The mean 24 h urinary Ca excretion rates (24 h UCaV) in hypertensive and normotensive subjects were 101 +/- 69 and 128 +/- 85 mg/day, respectively (n = 62, t = 1.378, p > 0.05). The mean serum Ca levels in HT was significantly decreased when compared with the controls (n = 26, t = 2.54, p < 0.05). In NT subjects systolic blood pressure (SBP) correlated positively with diastolic blood pressure (DBP) (r = 0.588) and UCaV (r = 0.516) and negatively with dietary Ca (r = -0.617, for all p < 0.05). In NT group DBP correlated positively with body mass index (BMI) (p < 0.05). In HT subjects, SBP correlated positively with DBP (r = 0.741) and negatively with serum Ca (r = -0.633), DBP also correlated negatively with serum Ca (r = 0.727). Among the 38 subjects, overnight calcium excretion rate (12 h UCaV) was correlated with the 24 h UCaV (y = 0.8279x + 42.735, r = 0.81, R-2 0.653, p < 0.05).
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    Nutritional Status and Magnesium Levels in Serum and Urine of Primary Hypertensives and Normotensives
    (ASIAN JOURNAL OF CHEMISTRY, 2011) Kayakirilmaz, Kadriye; Bayol, Emel; Yilmaz, Hatice Bal; Ariogul, Servet
    This research has been designed for the determination of the nutritional status, serum and urinary magnesium (UMg) levels and I correlation between urinary magnesium and blood pressure (BP). Thirty two volunteers' patients with essential hypertension (HT) and 35 normotensive (NT) control subjects, aged 21-79 years, have participated in this study. Fifty five subjects 24-h urinary samples were collected (28NT and 27HT). Besides, for determination of the correlation between 24 hUMgV and overnight excretion rate urinary magnesium (12 hUMgV), 43 urine samples were collected. Nutritional status was evaluated according to their food consumption and physical examination. After analyzing the collected blood and urinary samples, the mineral status was also evaluated. Among 13 hypertensive subjects three women had serum magnesium values lower than 1.7 mg Mg/dL (1.38-1.68 %). After 6 months treatment with magnesium, serum magnesium concentrations have increased to normal levels. In both groups blood pressure was positively correlated with UMgV and in hypertension group blood pressure was negatively correlated with serum magnesium levels (p < 0.05). Among the 43 subjects, 12 h UMgV was correlated with the 24 h UMgV and also in normotensive group UMgV was correlated positively with UCaV (p < 0.05). Overnight urinary magnesium excretion rate was correlated with the 24 h UMgV, so 12 h UMgV should be usually employable.