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    Isolated Bilateral Macular Edema due to Le Fort Type 1 and Mandibular Fracture: A Case Report
    (2022) Zor, Kürşat; Küçük, Erkut; Salbaş, Çiğdem Samur; Yıldırım, Gamze
    We report the diagnosis and follow-up process of a case who had bilateral macular edema after blunt facial trauma. A 36-year-old male patient with Le Fort type 1 and mandibular fracture without direct ocular trauma referred to the ophthalmology clinic. Visual acuity was 0.1 in both eyes according to Snellen chart. Ocular examination was normal except bilateral macular edema. The patient did not have any prior systemic or neurological diseases. The patient did not have cotton-wool spots, retinal hemorrhage, or Purtscher flecken in the fundus examination. He used topical 0.1% nepafenac solution for 1 month. Visual acuity returned to normal after complete resolution of the macular edema at 1 month and did not recur in the follow-up. We think that this case may be an isolated macular edema due to facial trauma or an atypical presentation of Purtscher retinopathy. Although facial fractures and trauma may cause Purtscher retinopathy with involvement of different retinal structures, the findings in this case suggest that isolated involvement of macula can also occur in these injuries.
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    The Inhibitory Effect of Capparis Ovata Polysaccharides on Cultured Pterygium Fibroblasts
    (2021) Küçük, Erkut; Zor, Kürşat; Aydemir, Işıl; Özkan, Oktay
    Objectives: Pterygium recurrence after removal surgery is an important problem. Polysaccharides obtained from Capparis species have been shown to possess various biological properties, including anti-tumor activity. This study was aninvestigation of the effect of Capparis ovata polysaccharides on cultured pterygium fibroblasts and a comparison with the effects of mitomycin C (MMC).Methods: Pterygium tissue samples were obtained during excision surgery from 3 patients with primary pterygium, and fibroblasts were isolated. Pterygium fibroblast cultures and L929 cell cultures were treated with different concentrations of MMC and Capparis ovata polysaccharides. Cell proliferation and migration were evaluated.Results: An MTT assay revealed that cell viability decreased with increasing concentrations of Capparis ovata polysaccharides in both cell types. MMC also inhibited the proliferation of both cell types. A scratch-wound assay indicated thatboth Capparis ovata polysaccharides and MMC molecules reduced proliferation and migration in the pterygium fibroblasts and L929 cells.Conclusion: The in vitro Capparis ovata polysaccharide inhibition of proliferation and migration of pterygium fibroblasts was similar to that of MMC. The results of this study suggested that Capparis ovata polysaccharides may be a valuable candidate drug to treat pterygium.
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    The Use of Androgens for Doping in Bodybuilding, and Ocular Side Effects: A Case Report
    (2022) Zor, Kürşat; Küçük, Erkut; Çınaroğlu, Selim; Yıldırım, Gamze
    Purpose: The androgenic steroids drostanolone, boldenone, and stanozolol are used off-label by athletes for doping. This is the second case reported in the literature who used these steroids as doping for bodybuilding and developed central serous chorioretinopathy (CSC) Cased presentation: A man aged 37 years presented with symptoms of unilateral metamorphopsia, slight central scotoma, and vision loss. The anamnesis revealed that the patient used steroids (drostanolone enanthate, boldenone undecylenate and stanozolol) for body building. He was diagnosed as having bilateral CSC. The symptoms were relieved in 2 months with of topical nepafenac treatment. Although the patient discontinued androgen steroids, recurrence of CSC observed 6 months later. Conclusions: This case is important in that it not only contributes to the ongoing debate in the literature that androgen steroids may be a risk factor for CSC formation, but also draws attention to the fact that in addition to known side effects drugs used for doping may have side effects that have not yet been reported.