Evaluation of subclinical left ventricular systolic dysfunction using two-dimensional speckle- tracking echocardiography in patients with non- alcoholic cirrhosis

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dc.contributor.authorAltekin R.E.
dc.contributor.authorCaglar B.
dc.contributor.authorKarakas M.S.
dc.contributor.authorOzel D.
dc.contributor.authorDeger N.
dc.contributor.authorDemir I.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2014
dc.departmentNiğde ÖHÜ
dc.description.abstractIntroduction: Cirrhosis is associated with certain abnormalities in left ventricular (LV) structure and function. Two-dimensional speckle-tracking echocardiography (2D-STE) enables a rapid and accurate analysis of regional LV systolic mechanics in the longitudinal, radial and circumferential directions. The aim of this study was to precisely assess the differences among the 3 directions in the early impairment of LV myocardial contraction in non-alcoholic cirrhotic patients with preserved LV pump function.Method: A total of 75 subjects, including 38 cirrhotic patients and 37 healthy individuals, were enrolled. Using 2D-STE, the strain (S) and systolic strain rate (SR<inf>S</inf>) values belonging to the radial (R), circumferential (C), and longitudinal (L) functions of the LV were measured.Results: In the cirrhotic group, the L<inf>S</inf>(20.57 ± 2.1 vs. 28.7 ± 43.1, p<0.001) and L<inf>SR-S</inf>(1.1 ± 0.24 vs. 1.6 ± 0.3) values were found to be lower, whereas the C<inf>S</inf>(24.82 ± 2.57 vs. 19.16 ± 4.58, p<0.001) and C<inf> SRS</inf>(1.41 ± 0.3 vs. 1.2 ± 0.4, p±0.004) values were found to be higher than in the healthy control group. The R<inf>S</inf>and R<inf>SR-S</inf>values did not differ among the groups. A relationship was observed between the MELD score, which shows the severity of the disease, and the C<inf>S</inf> value (â: 0.211, p<0.01, 95%CI: 0.086-0.503).Conclusion: LV myocardial contraction was impaired in the longitudinal direction. However, LV pump function was augmented by the circumferential shortening during the ventricular systole. Using the 2D-STE method for the regional evaluation of the LV, the LV damage can be detected in the subclinical phase in cirrhotic patients. © 2014, Hellenic Cardiological Society. All rights reserved.
dc.identifier.endpage410
dc.identifier.issn1109-9666
dc.identifier.issue5
dc.identifier.pmid25243439
dc.identifier.startpage402
dc.identifier.urihttps://hdl.handle.net/11480/752
dc.identifier.volume55
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherHellenic Cardiological Society
dc.relation.ispartofHellenic Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCirrhotic cardiomyopathy
dc.subjectStrain
dc.titleEvaluation of subclinical left ventricular systolic dysfunction using two-dimensional speckle- tracking echocardiography in patients with non- alcoholic cirrhosis
dc.typeArticle

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