Correlation of c-reactive protein and serum iron levels with syntax score

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dc.contributor.authorOzdemir, B.
dc.date.accessioned2024-11-07T10:39:38Z
dc.date.available2024-11-07T10:39:38Z
dc.date.issued2020
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractCardiovascular disease is one of the most common causes of morbidity and mortality in the world. Atherosclerosis is an inflammatory process, and serum C-reactive protein (CRP) is an acute-phase protein rising in response to inflammation. Serum iron (Fe) is one of the essential metals for the human body. Inflammation and infection are characterized by changes in Fe metabolism. Since atherosclerosis is an inflammatory process, changes in CRP and serum Fe levels are expected. However, the distribution of the disease in the coronary arteries is important for mortality and morbidity. The distribution of the disease can be determined by the syntax score. This study included 407 patients with a mean age of 56.4±10.7 years. The majority of the patients were male (51.4%). In this study, 53 and 354 patients had critical and no critical lesions, respectively. According to the baseline coronary angiograms, the syntax score was calculated in all patients. The laboratory variables, including hemoglobin levels, blood glucose, creatinine, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, Fe, and CRP were also evaluated in this study. Regarding the laboratory parameters of all groups, the mean CRP levels, Fe levels, and syntax score were estimated at 0.75±1.8 mg/dl, 80.4±27.5 mg/dl, and 1.5±4.8, respectively. Furthermore, a high syntax score correlated with Fe and CRP levels. Based on the findings of the present study, elevated serum Fe and CRP concentrations were associated with increased syntax score and atherosclerosis severity. © 2020 Razi Vaccine and Serum Research Institute. All rights reserved.
dc.identifier.doi10.22092/ari.2020.128122.1404
dc.identifier.endpage418
dc.identifier.issn0365-3439
dc.identifier.issue3
dc.identifier.pmid33025782
dc.identifier.scopus2-s2.0-85092067580
dc.identifier.scopusqualityQ3
dc.identifier.startpage413
dc.identifier.urihttps://doi.org/10.22092/ari.2020.128122.1404
dc.identifier.urihttps://hdl.handle.net/11480/11107
dc.identifier.volume75
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRazi Vaccine and Serum Research Institute
dc.relation.ispartofArchives of Razi Institute
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectAtherosclerosis
dc.subjectC-reactive protein
dc.subjectSerum iron
dc.subjectSyntax score
dc.titleCorrelation of c-reactive protein and serum iron levels with syntax score
dc.title.alternativeCorrélation du score syntaxique avec les taux de protéine c-réactive et de fer sérique
dc.typeArticle

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