The incidence and risk factors of severe retinopathy of prematurity in extremely low birth weight infants in Turkey

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dc.contributor.authorAli Riza Cenk C.
dc.contributor.authorPetricli I.S.
dc.contributor.authorHekimoglu E.
dc.contributor.authorDemirel N.
dc.contributor.authorBas A.Y.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2014
dc.departmentNiğde ÖHÜ
dc.description.abstractBackground: The aim of this study was to identify the incidence of severe retinopathy of prematurity (ROP) requiring laser treatment and the overall incidence of ROP in extremely low birth weight (ELBW) infants, and to evaluate the associated risk factors for developing severe ROP in ELBW infants in Turkey.Material/Methods: This retrospective, case-control, tertiary care-hospital based study included 235 ELBW infants screened for ROP. The incidence of the onset of ROP and severe ROP requiring laser treatment were assessed. The relationship between various clinical risk factors, and the development of severe ROP and onset of ROP were analyzed using univariate analysis and multivariate logistic regression analysis.Results: The overall incidence of any stage ROP and severe ROP requiring laser treatment in ELBW infants was 75.5% and 38.7%, respectively. Severe ROP requiring laser treatment in ELBW infants was significantly associated with various independent risk factors, including blood transfusion (P=0.002), gestational age at birth (P<0.001), gestational weight at birth (P=0.001), culture-proven sepsis (P=0.047).Conclusions: The severity of ROP may increase as weight at birth and gestational age at birth decrease, and in those with culture-proven sepsis as well as in those that receive blood transfusion. Clinicians should be aware of the presence of these risk factors when treating ELBW premature infants. Early detection and prevention of sepsis and reducing the number of blood transfusions may decrease the incidence of severe ROP requiring laser treatment. © Med Sci Monit, 2014.
dc.identifier.doi10.12659/MSM.892262
dc.identifier.endpage1653
dc.identifier.issn1234-1010
dc.identifier.pmid25220443
dc.identifier.startpage1647
dc.identifier.urihttps://dx.doi.org/10.12659/MSM.892262
dc.identifier.urihttps://hdl.handle.net/11480/708
dc.identifier.volume20
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherInternational Scientific Literature Inc.
dc.relation.ispartofMedical Science Monitor
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectExtremely premature
dc.subjectGestational age
dc.subjectInfant
dc.subjectPrevalence
dc.subjectRetinopathy of prematurity
dc.subjectRisk factors
dc.subjectTurkey
dc.titleThe incidence and risk factors of severe retinopathy of prematurity in extremely low birth weight infants in Turkey
dc.typeArticle

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