Pupillary response changes in Graves' disease

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dc.authoridOnder, Cagatay Emir/0000-0002-0293-2309
dc.contributor.authorBicer, Gamze Yildirim
dc.contributor.authorOnder, Cagatay Emir
dc.contributor.authorZor, Kursad Ramazan
dc.date.accessioned2024-11-07T13:25:14Z
dc.date.available2024-11-07T13:25:14Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPurpose: The aim of this study was to investigate pupillary contraction and dilatation response changes in Graves' disease. Materials and Methods: The patient group consisted of 55 euthyroid Graves patients and the control group consisted of 55 healthy individuals. Data from the right eyes of all participants were used. Static (scotopic, mesopic, photopic) and dynamic pupillometry measurements were performed with automatic pupillometry. The mean pupil dilatation speed was calculated according to dynamic measurements. Static measurements, dynamic measurements and the mean pupil dilatation speed data were compared between the patient and control groups.Results: There was no statistically significant difference between two groups in all static and dynamic values and the mean pupil dilatation speed. The mean scotopic pupil diameter was 5.41 & PLUSMN;0.776 mm in Graves' group and 5.55 & PLUSMN;0.747 mm in the control group. The mean mesopic pupil diameter was 4.39 & PLUSMN;0.721 in Graves' group and 4.17 & PLUSMN;0.640 mm in the control group. The mean photopic pupil diameter was 3.45 & PLUSMN;0,549 mm in Graves' group and 3.29 & PLUSMN;0.679 mm in the control group. The mean dynamic pupil diameter 0th second was 3, 54 & PLUSMN;0.541 mm in Graves' group and 3.48 & PLUSMN;0.708 mm in the control group. The mean speed of pupil dilatation at 18th second was 0.116 & PLUSMN;0.031 mm/sec in Graves' group and 0.128 & PLUSMN;0.040 mm/sec in the control group. Age was found to be an independent factor on pupillary parameters.Conclusion: The pupillary parameters of patients with euthyroid hormone levels were not affected. While pupillary responses appeared not to be affected in the case of euthyroidism, more studies including patients with hypothyroidism and hyperthyroidism are needed.
dc.identifier.doi10.17826/cumj.1229467
dc.identifier.endpage368
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue2
dc.identifier.startpage361
dc.identifier.urihttps://doi.org/10.17826/cumj.1229467
dc.identifier.urihttps://hdl.handle.net/11480/14563
dc.identifier.volume48
dc.identifier.wosWOS:001038321300006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherCukurova Univ, Fac Medicine
dc.relation.ispartofCukurova Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectAutonomic nervous system
dc.subjectGraves' disease
dc.subjectpupil dilatation speed
dc.subjectpupillometry
dc.subjectthyroid function tests
dc.titlePupillary response changes in Graves' disease
dc.typeArticle

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