Investigation of wet cupping therapy's effect on oxidative stress based on biochemical parameters

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dc.authoridengin, velittin selcuk/0000-0002-6338-4748
dc.authoridGozukara Bag, Harika Gozde/0000-0003-1208-4072
dc.authoridBenli, Ali Ramazan/0000-0003-0039-1497
dc.authoridErsoy, Suleyman/0000-0003-0001-9329
dc.authoridAltinoz, Eyup/0000-0002-3991-9773
dc.contributor.authorErsoy, Suleyman
dc.contributor.authorAltinoz, Eyup
dc.contributor.authorBenli, Ali Ramazan
dc.contributor.authorErdemli, Mehmet Erman
dc.contributor.authorAksungur, Zeynep
dc.contributor.authorBag, Harika Gozukara
dc.contributor.authorEngin, Velittin Selcuk
dc.date.accessioned2024-11-07T13:34:10Z
dc.date.available2024-11-07T13:34:10Z
dc.date.issued2019
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIntroduction: Wet cupping therapy is one of the main applications which has been used in the Unani medicine system. Current literature explaining how this traditional treatment method works is still limited. The aim of this study was to investigate whether wet cupping therapy could affect reactive oxygen species and antioxidant levels. Methods: This was a single arm pre and posttest intervention study conducted in Karabuk University Teaching and Research Hospital (KUTRH) between 1st January and 1st May 2018. Twenty-four participants were included. Wet Cupping Therapy was applied to all individuals once every month for three months. Venous blood samples were collected before the first (Venousl) and after the last application (Venous 2) and cupping blood samples were collected during the first and last applications. Malondialdehyde (MAD) and total oxidant status (TOS) which both indicate oxidation; glutathione (GSH), superoxide dismutase (SOD), total antioxidant status (TAS), catalase (CAT) activities that indicate antioxidant effect, and protein levels were measured on the obtained serums. Results: The highest MDA and TOS levels and the lowest TAS, GSH, SOD and CAT levels were found in initial cupping blood. Significant improvement was observed in second cupping blood for these parameters when compared to initial values. We also found that MDA and TOS levels, as well as TAS, GSH, SOD and CAT levels, all changed favorably in the Venous 2 blood sample compared to the Venous 1 (p < 0.001). Conclusion: Wet cupping therapy seems a promising method for increasing antioxidant levels and curbing oxidative stress.
dc.identifier.doi10.1016/j.eujim.2019.100946
dc.identifier.issn1876-3820
dc.identifier.issn1876-3839
dc.identifier.scopus2-s2.0-85069969285
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.eujim.2019.100946
dc.identifier.urihttps://hdl.handle.net/11480/15840
dc.identifier.volume30
dc.identifier.wosWOS:000492842100010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Inc
dc.relation.ispartofEuropean Journal of Integrative Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectWet cupping therapy
dc.subjectOxidative stress
dc.subjectMalondialdehyde
dc.subjectGlutathione
dc.subjectTotal oxidant status
dc.titleInvestigation of wet cupping therapy's effect on oxidative stress based on biochemical parameters
dc.typeArticle

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