Evaluation of Nosocomial Infections after ABO-Compatible and Incompatible Liver Transplantations

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dc.authoridKayabas, Uner/0000-0002-5323-0796
dc.contributor.authorBayar, Filiz Surucu
dc.contributor.authorBayindir, Yasar
dc.contributor.authorIsik, Burak
dc.contributor.authorOzgor, Dincer
dc.contributor.authorKayabas, Uner
dc.contributor.authorKuzucu, Cigdem
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-11-07T13:32:49Z
dc.date.available2024-11-07T13:32:49Z
dc.date.issued2018
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIntroduction: Liver transplantation is currently the only treatment option in acute hepatic failure and end-stage liver disease. In spite of their complications, ABO-incompatible liver transplantations are performed due to the shortage of suitable donors and the urgent need for organs. Despite developments in surgical techniques and improvements in antimicrobial prophylaxis strategies, infection is still an important complication and continues to be a major cause of death. In this study, ABO-compatible and ABO-incompatible liver transplant recipients were compared retrospectively in terms of infections and survival. Materials and Methods: Sixteen ABO-incompatible liver transplant recipients whose transplant surgeries were performed by the Liver Transplant Team between March 2002 and January 2011 were included in the study. ABO-compatible liver transplant recipients whose surgeries were undergone before and after the ABO-incompatible transplantation were selected as control group (total 32 patients). Patients' postoperative one year data were obtained from hospital records in both groups. Results: In the first postoperative year after liver transplantation, 12 (75%) of the ABO-incompatible recipients and 21 (65.6%) of the ABO-compatible recipients experienced at least one infection attack (p=0.509). The infection attack rate was 175% in the ABO-incompatible group and 113% in the ABO-compatible group (p=0.262). Eight (50%) of the 16 ABO-incompatible recipients and nine (28.1%) of the 32 ABO-compatible recipients died within one year of transplantation (p=0.135). There were no statistically significant differences between the groups in terms of mortality or infection rates. Pseudomonas aeruginosa was the most common isolate in both ABO-compatible and incompatible recipients. Conclusion: The findings of the study showed that ABO-incompatible transplants were comparable to ABO-compatible transplants in terms of infection rates and survival. It should be kept in mind that ABO-incompatible liver transplantation may be an option, especially in emergencies and in selected cases, despite differences in complications between centers and patient groups and concerns about greater complications in ABO-incompatible patients. However, further studies are needed on this topic.
dc.identifier.doi10.4274/mjima.2018.14
dc.identifier.issn2147-673X
dc.identifier.urihttps://doi.org/10.4274/mjima.2018.14
dc.identifier.urihttps://hdl.handle.net/11480/15636
dc.identifier.volume7
dc.identifier.wosWOS:000463053800005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofMediterranean Journal of Infection Microbes and Antimicrobials
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectABO-incompatible and compatible liver transplantation
dc.subjectinfection
dc.subjectsurvival
dc.titleEvaluation of Nosocomial Infections after ABO-Compatible and Incompatible Liver Transplantations
dc.typeArticle

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