Histomorphometrical and radiological comparison of low-level laser therapy effects on distraction osteogenesis: experimental study

Basit Öğe Kaydı
dc.authorid0000-0001-6980-2085
dc.authorid0000-0002-7553-3915
dc.contributor.authorKan, Bahadir
dc.contributor.authorTasar, Ferda
dc.contributor.authorKorkusuz, Petek
dc.contributor.authorErsoy, Orkun
dc.contributor.authorCetinkaya, Alper
dc.contributor.authorGur, Cagla Z.
dc.contributor.authorMeral, Gokce
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2014
dc.departmentNiğde ÖHÜ
dc.description.abstractDistraction osteogenesis (DO) is the application of traction to the callus formed between bone segments and stimulation of bone formation by creating stress on the callus with this traction. Shorten the duration of DO and increasing the capacity of bone formation is important to prevent the possible complications of DO. For this reason, it was considered that low-level laser therapy (LLLT) may affect positively DO and it can decrease the complication range by shortening the period. Unilateral mandibular distractors were applied on 16 female white New Zealand rabbit to prove this hypothesis with micro CT, plain radiograph and histomorphometric analyses. Eight rabbits were applied LLLT with GaAlAs laser on the distraction area during the distraction period. On the post-distraction 28th day, four rabbits from study group and four rabbits from control groups were sacrificed. The rest of the rabbits were sacrificed on post-distraction 56th day. As a result of this study, significant positive effects of LLLT on post-distraction 28th day were revealed with all analyses. In histomorphometrical analyses, new bone formation was significantly higher in short-term laser applied group comparing to that of short-term control group (p = 0.029). In both microCT and plain radiograph, the highest radioopacity values were observed in short-term laser group when compared with that of the controls (p = 0.043 and p = 0.025, respectively). Even though LLLT increased the healing capacity on short-term, it was not sufficient on long-term (post-distraction 56th day) healing. LLLT application on distraction period, activate healing on bone so it may decrease DO period. The result of this study should be supported with clinical studies and the most effective laser source, dose and application time should be revealed with experimental and clinical studies.
dc.description.sponsorshipHacettepe University Scientific Research Unit Research Grant
dc.description.sponsorshipThis research was supported by Hacettepe University Scientific Research Unit Research Grant.
dc.identifier.doi10.1007/s10103-013-1308-3
dc.identifier.endpage220
dc.identifier.issn0268-8921
dc.identifier.issn1435-604X
dc.identifier.issue1
dc.identifier.pmid23604845
dc.identifier.scopus2-s2.0-84893706785
dc.identifier.scopusqualityQ2
dc.identifier.startpage213
dc.identifier.urihttps://dx.doi.org/10.1007/s10103-013-1308-3
dc.identifier.urihttps://hdl.handle.net/11480/4295
dc.identifier.volume29
dc.identifier.wosWOS:000329834200028
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherSPRINGER LONDON LTD
dc.relation.ispartofLASERS IN MEDICAL SCIENCE
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDistraction osteogenesis
dc.subjectLow level laser therapy
dc.subjectBone
dc.subjectRabbit
dc.subjectMandible
dc.titleHistomorphometrical and radiological comparison of low-level laser therapy effects on distraction osteogenesis: experimental study
dc.typeArticle

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