The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
Küçük Resim Yok
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Publications Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). Methods: 78 (27 women, mean age 43.95 +/- 7.28) patients with CSF, and 70 (22 women, mean age 44.34 +/- 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-beta and aortic distensibility) were evaluated in both groups. Results: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-beta values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-beta. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-beta was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001). Conclusion: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology.
Açıklama
Anahtar Kelimeler
Coronary slow flow, arterial stiffness, carotid-femoral pulse wave velocity, aortic elastic properties
Kaynak
Jrsm Cardiovascular Disease
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
9