Relationship between total thiol status and thrombocytopenia in patients with Crimean-Congo hemorrhagic fever

Basit Öğe Kaydı
dc.contributor.authorGuner R.
dc.contributor.authorTasyaran M.A.
dc.contributor.authorKeske S.
dc.contributor.authorHasanoglu I.
dc.contributor.authorKalem A.K.
dc.contributor.authorYapar D.
dc.contributor.authorErel O.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2012
dc.departmentNiğde ÖHÜ
dc.description.abstractThe objective of this study was to investigate the relationship between serum total thiol level and total oxidant status (TOS) and thrombocytopenia among patients with Crimean-Congo hemorrhagic fever (CCHF). Eighty-three subjects and 56 controls were enrolled in the study. Thiol levels were measured with the DTNB method and TOS was measured with the Erel's method among subjects and controls. Thiol levels were lower in subjects than controls and TOS levels were higher in subjects than controls. There was a significant correlation between total thiol levels and platelet counts (r=0.84, p<0.0001) among subjects. Further investigations are needed into the link between total thiol level and TOS and the pathogenesis of hemorrhage in CCHF.
dc.identifier.endpage1418
dc.identifier.issn0125-1562
dc.identifier.issue6
dc.identifier.pmid23413704
dc.identifier.startpage1411
dc.identifier.urihttps://hdl.handle.net/11480/881
dc.identifier.volume43
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.relation.ispartofSoutheast Asian Journal of Tropical Medicine and Public Health
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAPTT
dc.subjectCrimean-Congo hemorrhagic fever
dc.subjectThiol
dc.subjectThrombocytopenia
dc.subjectTOS
dc.titleRelationship between total thiol status and thrombocytopenia in patients with Crimean-Congo hemorrhagic fever
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu