Bioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetes

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dc.authoridKonca, Yusuf/0000-0002-6231-1512
dc.authoridAhhmed, Abdulatef/0000-0001-6686-0271
dc.authoridBASYIGIT, Bulent/0000-0002-6617-1836
dc.authoridCam, Mustafa/0000-0003-1258-0834
dc.authoridYilmaztekin, Murat/0000-0002-5667-9169
dc.authoridALASALVAR, Hamza/0000-0003-3000-7310
dc.contributor.authorCam, Mustafa
dc.contributor.authorBasyigit, Bulent
dc.contributor.authorAlasalvar, Hamza
dc.contributor.authorYilmaztekin, Murat
dc.contributor.authorAhhmed, Abdulatef
dc.contributor.authorSagdic, Osman
dc.contributor.authorKonca, Yusuf
dc.date.accessioned2024-11-07T13:35:17Z
dc.date.available2024-11-07T13:35:17Z
dc.date.issued2020
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPeppermint and spearmint, both members of the Lamiaceae family, have been used in the form of extracts, infusions, and decoctions, because of their health benefits. Consumers are looking for functional food products which not only provide health benefits but also necessitate less preparation time. Therefore, this study aimed to investigate the bioactive properties of powdered peppermint and spearmint extracts. Peppermint and spearmint extracts obtained using pressurized water extraction were made into powder forms with a spray dryer using the air inlet temperature of 140 degrees C. Powdered peppermint extract (PPE) and powdered spearmint extract (PSE) showed significant inhibition against key enzymes of type 2 diabetes (alpha-glucosidase) and hypertension (angiotensin 1-converting enzyme, ACE). Alpha glucosidase inhibition degree of PPE and PSE as IC50 values was 0.6 and 1.2 mg/mL, respectively, while IC50 values for the ACE inhibition test were 4.5 mg for PPE and 5.8 mg for PSE. The HPLC-DAD method for ACE inhibition activity showed the suitability of this method for plant extracts high in phenolics which had no interference effects on the results. There were no differences between PPE and PSE in the DPPH test. However, PPE had higher Trolox equivalent antioxidant capacity (190 mg/g) with the ABTS test than PSE (170 mg/g). The predominant phenolics of PPE and PSE were found to be eriocitrin (47 mg/g) and rosmarinic acid (27 mg/g), respectively.
dc.description.sponsorshipScientific and Research Council of Turkey (TUBITAK) [113O471]
dc.description.sponsorshipThis work was financially supported by the Scientific and Research Council of Turkey (TUBITAK) under the Project Number of 113O471.
dc.identifier.doi10.1016/j.fbio.2020.100577
dc.identifier.issn2212-4292
dc.identifier.issn2212-4306
dc.identifier.scopus2-s2.0-85082629524
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.fbio.2020.100577
dc.identifier.urihttps://hdl.handle.net/11480/16428
dc.identifier.volume35
dc.identifier.wosWOS:000535177600025
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofFood Bioscience
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectMentha piperita
dc.subjectMentha spicata
dc.subjectAlpha-glucosidase
dc.subjectAngiotensin 1-converting enzyme
dc.subjectEriocitrin
dc.subjectRosmarinic acid
dc.titleBioactive properties of powdered peppermint and spearmint extracts: Inhibition of key enzymes linked to hypertension and type 2 diabetes
dc.typeArticle

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