Identification of immunohistochemical localization of irisin in the dwarf hamster (Phodopus roborovskii) tissues

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dc.authoridTARAKCI GENCER, BERRIN/0000-0002-5931-9919
dc.authoridGUR, FATIH MEHMET/0000-0001-7748-3272
dc.contributor.authorGur, F. M.
dc.contributor.authorTimurkaan, S.
dc.contributor.authorTarakci, B. Gencer
dc.contributor.authorYalcin, M. H.
dc.contributor.authorOzkan, Z. E.
dc.contributor.authorBaygeldi, S. B.
dc.contributor.authorYilmaz, S.
dc.date.accessioned2024-11-07T13:32:07Z
dc.date.available2024-11-07T13:32:07Z
dc.date.issued2018
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIrisin is mainly secreted by heart and skeletal muscle cells. It is an exercise-induced protein that converts white adipose tissue to brown. Increased irisin expression was lead to weight loss and improved glucose tolerance. We investigated irisin immunoreactivity in various tissues of the dwarf hamsters (Phodopus roborovskii). Tissues were processed, embedded in paraffin, sectioned at 5m and stained immunohistochemically for irisin. In the retina, irisin was found almost all layers, except outer nuclear layer. Also, irisin immunoreactivity was observed in the skin, cornea, striated muscle, parotid gland, tongue, oesophagus, stomach and small intestine. The findings from this study support the notion that skeletal muscle is not the primary source of irisin.
dc.identifier.doi10.1111/ahe.12345
dc.identifier.endpage179
dc.identifier.issn0340-2096
dc.identifier.issn1439-0264
dc.identifier.issue2
dc.identifier.pmid29527793
dc.identifier.scopus2-s2.0-85043489593
dc.identifier.scopusqualityQ2
dc.identifier.startpage174
dc.identifier.urihttps://doi.org/10.1111/ahe.12345
dc.identifier.urihttps://hdl.handle.net/11480/15244
dc.identifier.volume47
dc.identifier.wosWOS:000427111900012
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofAnatomia Histologia Embryologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectcornea
dc.subjectirisin
dc.subjectretina
dc.subjectskin
dc.subjectsmall intestine
dc.subjectstomach
dc.subjectstriated muscle
dc.titleIdentification of immunohistochemical localization of irisin in the dwarf hamster (Phodopus roborovskii) tissues
dc.typeArticle

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