Determination of anti-oxidative, anti-microbial activity and heavy metal contents of Leucoagaricus leucothites

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dc.contributor.authorSevindik M.
dc.contributor.authorRasul A.
dc.contributor.authorHussain G.
dc.contributor.authorAnwar H.
dc.contributor.authorZahoor M.K.
dc.contributor.authorSarfraz I.
dc.contributor.authorSelamoglu Z.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2018
dc.departmentNiğde ÖHÜ
dc.description.abstractMushrooms, a treasure of diverse bioactive scaffolds, have been widely admired due to their nutritional and medicinal significance all over the world. The current study intended to evaluate the therapeutic potentiality of an edible mushroom, Leucoagaricus leucothites (Vittad.) Wasser. Thus, anti-oxidant potential of L. leucothites was determined using DPPH assay and for the determination of anti-microbial potential agar dilution procedure was followed. TOS (total oxidant status), TAS (total anti-oxidant status), and OSI (oxidative stress index) values were evaluated utilizing Rel Assay Kits. For the assessment of heavy metal contents, wet decomposition approach with atomic absorption spectrophotometry was adopted. Screening of phytochemicals present in ethanolic extract of L. leucothites were determined by HPLC. TAS, TOS and OSI values were found to be 8.291mmol/L, 10.797µmol/L and 0.130 respectively. Our results declared that heavy metal contents are generally in the safe range. Phytochemical analysis of L. leucothites has affirmed the presence of important phenolics such as gallic acid, catechin, and hesperidin. Investigations on anti-oxidant and anti-microbial potential of L. leucothites has uncovered the fact that this naturally occurring, biologically active, and therapeutically effective mushroom specie has natural borne anti-oxidant and anti-microbial potential and it would be worthwhile to use it for nutritional as well as medicinal purpose.
dc.identifier.endpage2168
dc.identifier.issn1011601X
dc.identifier.issue5
dc.identifier.pmid30393228
dc.identifier.scopus2-s2.0-85056278413
dc.identifier.scopusqualityN/A
dc.identifier.startpage2163
dc.identifier.urihttps://hdl.handle.net/11480/1613
dc.identifier.volume31
dc.identifier.wosWOS:000447576200023
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherNLM (Medline)
dc.relation.ispartofPakistan journal of pharmaceutical sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.titleDetermination of anti-oxidative, anti-microbial activity and heavy metal contents of Leucoagaricus leucothites
dc.typeArticle

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