Eupatilin: a natural pharmacologically active flavone compound with its wide range applications

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dc.authoridRiaz, Ammara/0000-0001-5025-9182
dc.authoridHUSSAIN, Ghulam/0000-0001-9090-7789
dc.authoridSelamoglu, Zeliha/0000-0001-9056-6435
dc.contributor.authorNageen, Bushra
dc.contributor.authorSarfraz, Iqra
dc.contributor.authorRasul, Azhar
dc.contributor.authorHussain, Ghulam
dc.contributor.authorRukhsar, Fariha
dc.contributor.authorIrshad, Somia
dc.contributor.authorRiaz, Ammara
dc.date.accessioned2024-11-07T13:32:26Z
dc.date.available2024-11-07T13:32:26Z
dc.date.issued2020
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractEupatilin (5,7-dihydroxy-3 ',4 ',6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupatilin could be subjected to structural optimization for the synthesis of derivative analogs to reinforce its efficacy, to minimize toxicity, and to optimize absorption profiles, which will ultimately lead towards potent drug candidates. Although, reported data acclaim multiple pharmacological activities of eupatilin but further experimentations on its molecular mechanism of action are yet mandatory to elucidate full spectrum of its pharmacological activities.
dc.identifier.doi10.1080/10286020.2018.1492565
dc.identifier.endpage16
dc.identifier.issn1028-6020
dc.identifier.issn1477-2213
dc.identifier.issue1
dc.identifier.pmid29973097
dc.identifier.scopus2-s2.0-85077618199
dc.identifier.scopusqualityQ2
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1080/10286020.2018.1492565
dc.identifier.urihttps://hdl.handle.net/11480/15421
dc.identifier.volume22
dc.identifier.wosWOS:000505656500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal of Asian Natural Products Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectEupatilin
dc.subjectanti-cancer
dc.subjectanti-inflammatory
dc.subjectanti-oxidant
dc.subjectmedicinal plants
dc.subjectflavone
dc.titleEupatilin: a natural pharmacologically active flavone compound with its wide range applications
dc.typeArticle

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