Evaluation of the relationship between disease severity and the leptin, adiponectin, and chemerin levels in overweight and obese COVID-19 patients

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dc.authoridSEYDEL, GONUL SEYDA/0000-0001-9317-0719
dc.authoridEryilmaz-Eren, Esma/0000-0002-2712-9694
dc.contributor.authorSeydel, Gonul Seyda
dc.contributor.authorGunturk, Inayet
dc.contributor.authorYazici, Cevat
dc.contributor.authorTopaloglu, Ulas Serkan
dc.contributor.authorEren, Esma Eryilmaz
dc.contributor.authorYuksel, Recep Civan
dc.date.accessioned2024-11-07T13:32:34Z
dc.date.available2024-11-07T13:32:34Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractAim: Overweight and obesity are substantial risk factors in the severity of COVID-19 disease. This study aimed to assess the relationship between the disease severity and leptin, adiponectin, and chemerin levels in overweight and obese COVID-19 patients. Material and Methods: The study involved 60 COVID-19 patients (patient group) and 30 healthy controls with BMI >= 25. The patient group was split into two subgroups based on disease severity (30 mild/moderate and 30 severe/critical patients). The levels of leptin, adiponectin, and chemerin in plasma were determined using the ELISA technique. Results: Our study revealed that leptin levels were considerably increased in both groups of COVID-19 patients compared to the healthy controls, while chemerin levels were decreased. In adiponectin levels, there was no statistically significant difference between the groups. Discussion: Plasma leptin and chemerin levels are associated with the progression and/or severity of disease in overweight and obese COVID-19 patients.
dc.description.sponsorshipNigde Omer Halisdemir University Scientific Research Projects Coordination Unit [SAT 2022/3-BAGEP]
dc.description.sponsorshipThis work was supported by the Nigde Omer Halisdemir University Scientific Research Projects Coordination Unit under Project number: SAT 2022/3-BAGEP.
dc.identifier.doi10.4328/ACAM.22078
dc.identifier.endpage333
dc.identifier.issn2667-663X
dc.identifier.issue5
dc.identifier.startpage329
dc.identifier.urihttps://doi.org/10.4328/ACAM.22078
dc.identifier.urihttps://hdl.handle.net/11480/15490
dc.identifier.volume15
dc.identifier.wosWOS:001222910000009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherBayrakol Medical Publisher
dc.relation.ispartofAnnals of Clinical and Analytical Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectCOVID-19
dc.subjectLeptin
dc.subjectAdiponectin
dc.subjectChemerin
dc.subjectObesity
dc.titleEvaluation of the relationship between disease severity and the leptin, adiponectin, and chemerin levels in overweight and obese COVID-19 patients
dc.typeArticle

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