Association of amoxicillin use and molar incisor hypomineralization in piglets: Visual and mineral density evaluation

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dc.contributor.authorKuscu, Ozgur Onder
dc.contributor.authorSandalli, Nuket
dc.contributor.authorDikmen, SerdaI
dc.contributor.authorErsoy, Orkun
dc.contributor.authorTatar, Ilkan
dc.contributor.authorTurkmen, Ismet
dc.contributor.authorCaglar, Esher
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2013
dc.departmentNiğde ÖHÜ
dc.description.abstractAim: The aim of the present study was to determine the prevalence of MIH both visually and quantitatively, and describes the range of mineral densities of enamel specimens from three groups of piglets where two groups were given different doses of amoxicillin in infancy. Methods: In this blind randomized clinical study, 20 piglets were randomly divided into three groups. Group A received a standard dose (50 mg/kg/day) and Group B received a high dose (90 mg/kg/day) of amoxicillin in selected days of the month (20 working days) they were born. Group K did not receive any medication and served as control. Thirteen right mandibular permanent first molars (PFMs) were randomly collected from 3 groups of piglets at age 10 months for evaluation under X-ray micro-tomography. Tomographic data were obtained using a Skyscan 1174 compact micro-CT in the Department of Anatomy. Results: Prevalence of MIH was 0% in all groups. MD values were quantified after enamel grey level (0-255) measurements on horizontal cross-sectional slices. After MD measurements, the effects of amoxicillin use on MIH are presented. Conclusions: While MIH is a multifactorial disturbance, the present study attempted to highlight the clinical findings of a possible relationship between amoxicillin use and MIH with the aid of X-ray micro-tomography. (C) 2013 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.archoralbio.2013.04.012
dc.identifier.endpage1433
dc.identifier.issn0003-9969
dc.identifier.issn1879-1506
dc.identifier.issue10
dc.identifier.pmid23870729
dc.identifier.scopus2-s2.0-84888040139
dc.identifier.scopusqualityQ2
dc.identifier.startpage1422
dc.identifier.urihttps://dx.doi.org/10.1016/j.archoralbio.2013.04.012
dc.identifier.urihttps://hdl.handle.net/11480/4345
dc.identifier.volume58
dc.identifier.wosWOS:000325236600019
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartofARCHIVES OF ORAL BIOLOGY
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAmoxicillin
dc.subjectDental hypomineralization
dc.subjectEnamel hypomineralization
dc.subjectIncisor
dc.subjectMolar
dc.subjectPenicillin V
dc.subjectPig
dc.titleAssociation of amoxicillin use and molar incisor hypomineralization in piglets: Visual and mineral density evaluation
dc.typeArticle

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