Evaluation of Laboratory Parameters as Predictors of Mortality

dc.authoridAltun, Yasin/0000-0002-1521-4349
dc.contributor.authorAltun, Yasin
dc.contributor.authorBalci, Halime D.
dc.date.accessioned2024-11-07T13:25:20Z
dc.date.available2024-11-07T13:25:20Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractBackground: Evaluation of biomarkers as risk factors for mortality may provide early intervention and treatment for fatal diseases. We aimed to determine the usability of inexpensive and easily measurable tests in the differentiation of critically ill patients by investigating their relationship with mortality. Methods: This study was executed by examining the sixth, third, and first month examinations of patients registered to the home health care services unit in 2022 before mortality due to any reason. This study was conducted by including 1,060 patients. All parameters were distributed non-parametrically. The difference between the dependent groups was evaluated with Friedman's two-way analysis of variance, and p < 0.05 was considered statistically significant. Results: When the patients' premortem one-month, three-month, and six-month results were examined, there was an increase in mean platelet volume (MPV) values over time. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) also increased. In these two parameters, the difference between the first and third months and between the first and sixth months was statistically significant. Given the C-Reactive Protein (CRP)/Albumin Ratio (CAR) and CRP/Prealbumin results, a significant increase was observed in both ratios. A more than four-fold increase was observed in the CAR between the premortem first and sixth month results, which increased gradually over time and was statistically significant. Conclusions: NLR, PLR, MPV, CAR and CRP/Prealbumin values were statistically associated with mortality.
dc.identifier.doi10.7754/Clin.Lab.2023.230811
dc.identifier.endpage669
dc.identifier.issn1433-6510
dc.identifier.issue4
dc.identifier.pmid38623656
dc.identifier.scopus2-s2.0-85190819048
dc.identifier.scopusqualityQ3
dc.identifier.startpage664
dc.identifier.urihttps://doi.org/10.7754/Clin.Lab.2023.230811
dc.identifier.urihttps://hdl.handle.net/11480/14646
dc.identifier.volume70
dc.identifier.wosWOS:001226387500006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherClin Lab Publ
dc.relation.ispartofClinical Laboratory
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectmortality
dc.subjectbiomarker
dc.subjectneutrophil
dc.subjectlymphocyte
dc.titleEvaluation of Laboratory Parameters as Predictors of Mortality
dc.typeArticle

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