Antioxidative role of selenium against the toxic effect of heavy metals (Cd+2 Cr+3 on liver of rainbow trout (Oncorhynchus mykiss Walbaum 1792)

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dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorOrun, Ibrahim
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorErdogan, Kenan
dc.contributor.authorAlkan, Aysel
dc.contributor.authorYilmaz, Ismet
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2008
dc.departmentNiğde ÖHÜ
dc.description.abstractThe main purpose of this study is to discuss the effect of Cd+2, Cr+3 and Se metals on biochemical parameters in liver tissue of Oncorhynchus mykiss. The rainbow trout were exposed to heavy metal stress ( Cd+2, Cr+3) at 2 ppm dosage. The present study was undertaken to determine the protective effect of selenium treatment at the same dosage ( 2 ppm) on some biochemical parameters. The activity of catalase ( CAT), glutathione peroxidase ( GSH-Px), superoxide dismutase ( SOD) and the changes in levels of malondialdehyde ( MDA) from biochemical parameters were determined in liver tissue of the fish groups exposed to heavy metals, especially for the selenium-applied groups. Results of this study showed that the activities of CAT, GSH-Px and SOD in the tissues of fish exposed to the stress of Cd+2 and Cr+3 were significantly lower than the control groups ( P < 0.05). Meanwhile, the closer values to the control groups were obtained in selenium-added groups ( Cr+3 + Se+4, Cd+2 + Se+4). For the level of MDA, the last production of lipid peroxidation showed increases ( P < 0.05) in the groups exposed to the metal stress, whereas significant decreases were obtained in selenium-applied groups. The result of the statistical evaluation showed that the negative effects occurring in the biochemical parameters of the applied groups exposed to the toxicity of heavy metal were significantly eliminated ( P < 0.05) as a result of selenium treatment.
dc.identifier.doi10.1007/s10695-007-9179-9
dc.identifier.endpage222
dc.identifier.issn0920-1742
dc.identifier.issn1573-5168
dc.identifier.issue3
dc.identifier.pmid18665459
dc.identifier.scopus2-s2.0-48649087993
dc.identifier.scopusqualityQ1
dc.identifier.startpage217
dc.identifier.urihttps://dx.doi.org/10.1007/s10695-007-9179-9
dc.identifier.urihttps://hdl.handle.net/11480/5203
dc.identifier.volume34
dc.identifier.wosWOS:000258086500004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherSPRINGER
dc.relation.ispartofFISH PHYSIOLOGY AND BIOCHEMISTRY
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntioxidant enzyme
dc.subjectHeavy metal (Cd+2, Cr+3)
dc.subjectLipid peroxidation
dc.subjectLiver
dc.subjectOncorhynchus mykiss
dc.subjectOxidative stress
dc.subjectSelenium
dc.titleAntioxidative role of selenium against the toxic effect of heavy metals (Cd+2 Cr+3 on liver of rainbow trout (Oncorhynchus mykiss Walbaum 1792)
dc.typeArticle

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