Oxytocin and Vasopressin Levels and Related Factors in Adolescents with Social Phobia and Other Anxiety Disorders

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dc.authoridUzun, Necati/0000-0003-3381-2331
dc.authoridBalci, Tevfik/0000-0001-6212-0444
dc.authoridAKCA, OMER FARUK/0000-0002-9712-1874
dc.contributor.authorUzun, Necati
dc.contributor.authorAkca, Omer Faruk
dc.contributor.authorKilinc, Ibrahim
dc.contributor.authorBalci, Tevfik
dc.date.accessioned2024-11-07T13:32:05Z
dc.date.available2024-11-07T13:32:05Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: This study aimed to determine whether a difference exists in plasma oxytocin and vasopressin levels among social anxiety disorder, other anxiety disorders, and healthy control groups in adolescents. The relationship between several psychiatric variables (i.e., state and trait anxiety, social anxiety, childhood trauma, and behavioral inhibition) and oxytocin or vasopressin levels were also investigated in adolescents with anxiety disorders. Methods: The study included three groups of adolescents: social anxiety disorder (n = 29), those with other anxiety disorders (n = 27), and the control group (n = 28). The participants filled out self-report scales to determine various psychological variables. Oxytocin and vasopressin levels were determined from the blood samples of the participants. Results: The oxytocin levels did not show a significant difference between the social anxiety disorder group and the other anxiety disorders group. However, the oxytocin levels were significantly higher in the social anxiety disorder and other anxiety disorders groups than in the control group. The vasopressin levels did not show a significant difference among the groups. According to the hierarchical regression analysis, the state and trait anxiety levels predicted oxytocin in opposite directions. Oxytocin showed positive and negative relationship with trait and state anxiety respectively. No predictive factors were found for the vasopressin levels. Conclusion: We found that the oxytocin levels of adolescents with social anxiety disorder were not different from those of adolescents with other anxiety disorders. Further studies can improve our knowledge of the relationship among anxiety disorders and oxytocin or vasopressin.
dc.description.sponsorshipScientific Research Project Coordination Unit of Necmettin Erbakan University [161518023]
dc.description.sponsorshipFunding for this study was provided by a grant from the Scientific Research Project Coordination Unit of Necmettin Erbakan University (Project no. 161518023).
dc.identifier.doi10.9758/cpn.2022.20.2.330
dc.identifier.endpage342
dc.identifier.issn1738-1088
dc.identifier.issn2093-4327
dc.identifier.issue2
dc.identifier.pmid35466104
dc.identifier.scopus2-s2.0-85132593957
dc.identifier.scopusqualityQ2
dc.identifier.startpage330
dc.identifier.urihttps://doi.org/10.9758/cpn.2022.20.2.330
dc.identifier.urihttps://hdl.handle.net/11480/15223
dc.identifier.volume20
dc.identifier.wosWOS:000792520700003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKorean Coll Neuropsychopharmacology
dc.relation.ispartofClinical Psychopharmacology and Neuroscience
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectAnxiety disorders
dc.subjectBehavioral inhibition
dc.subjectOxytocin
dc.subjectSocial phobia
dc.subjectVasopressin
dc.titleOxytocin and Vasopressin Levels and Related Factors in Adolescents with Social Phobia and Other Anxiety Disorders
dc.typeArticle

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