A comparison of the measurements with biochemical markers of bone turnover and bone mineral density in the assessment of the efficiency of osteoporosis treatment [Osteporoz tedavisinin etkinliginin degerlendirilmesinde kemik döngüsü biyokimyasal belirteçleri ve kemik mineral yogunlugu ölçümlerinin karşilaştirilmasi]

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dc.contributor.authorBaybars Ataoglu M.
dc.contributor.authorŞahap Atik O.
dc.contributor.authorGül O.
dc.contributor.authorSarikaya B.
dc.contributor.authorGörmeli G.
dc.contributor.authorÖztürk B.Y.
dc.contributor.authorÖzgürol B.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2013
dc.departmentNiğde ÖHÜ
dc.description.abstractObjectives: This study aims to compare the measurements using biochemical markers of bone turnover and bone mineral density (BMD) in the assessment of the efficiency of osteoporosis treatment. Patients and methods: Between March 2006 and December 2008, 166 patients with osteoporosis in our clinic were included. Patients who were out of contact due to death or other reasons during follow-up were excluded. We compared the measurements of urinary biochemical markers of bone turnover using cross-linked N-telopeptide (Ntx) values and BMD in 60 patients (49 females, 11 males; mean age: 65.7 years; range: 42 to 87 years) with osteoporosis who were treatment-naive and completed study. Results: Twenty-nine (48.3%) of the patients received surgical treatment, while 31 (51.7%) received conservative therapy. Urine NTx values of the patients decreased 38.82% at three months; 51.99% at six months and 66.41% at 12 months. Lumbar vertebra BMD increased by 20.7% and femur neck BMD increased by 11.9% at the end of the first year. Conclusion: Urine NTx values respond to osteoporosis treatment faster than BMD measurements; thereby it may be suitable to use this parameter for the monitorization of the treatment efficiency.
dc.identifier.doi10.5606/ehc.2013.19
dc.identifier.endpage86
dc.identifier.issn1305-8282
dc.identifier.issue2
dc.identifier.startpage82
dc.identifier.urihttps://dx.doi.org/10.5606/ehc.2013.19
dc.identifier.urihttps://hdl.handle.net/11480/827
dc.identifier.volume24
dc.institutionauthor[0-Belirlenecek]
dc.language.isotr
dc.relation.ispartofEklem Hastaliklari ve Cerrahisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBone mineral density
dc.subjectCross-linked N-telopeptide
dc.subjectOsteoporosis
dc.subjectUrine
dc.titleA comparison of the measurements with biochemical markers of bone turnover and bone mineral density in the assessment of the efficiency of osteoporosis treatment [Osteporoz tedavisinin etkinliginin degerlendirilmesinde kemik döngüsü biyokimyasal belirteçleri ve kemik mineral yogunlugu ölçümlerinin karşilaştirilmasi]
dc.typeArticle

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