Synthesis, antioxidant and anti-microbial properties of two organoselenium compounds

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dc.authorid0000-0001-6080-229X
dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorGok, Yetkin
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorAtes, Burhan
dc.contributor.authorGunal, Selami
dc.contributor.authorYilmaz, Ismet
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2015
dc.departmentNiğde ÖHÜ
dc.description.abstractThe aim of this study is synthesis of two different series of organoselenium compounds and available in vitro antioxidant and antimicrobial properties of thee synthetic compounds. The synthetic compounds were identified by H-1-NMR (300 MHz), C-13-NMR (75.5 MHz), FT-IR spectroscopic techniques and micro analysis. Antioxidant properties of two synthetic organoselenium compounds were determined by 1,1- dipheny1-2-picrylhydrazyl (DPPH) radical method, reducing power assay and beta-carotene bleaching method as in vitro. Antimicrobial effects of samples were assessed by the agar dilution procedure and using gram positive and gram-negative bacteria and yeast strains. Although 1,3-di-pmethoxybenzylpyrimidine-2-selenone showed better antiradical activity in DPPH test and higher protective activity on beta-carotene, 1-isopropyl-3-methylbenzimidazole-2-selenone was found to be better in reducing power and antimicrobial activity.
dc.description.sponsorshipTechnological and Scientific Research Council of Turkey TUBITAK [TBAG-2259 (102T185)]
dc.description.sponsorshipWe thank to Technological and Scientific Research Council of Turkey TUBITAK TBAG-2259 (102T185) for financial support of this work.
dc.identifier.endpage616
dc.identifier.issn1011-601X
dc.identifier.issue2
dc.identifier.pmid25730792
dc.identifier.scopus2-s2.0-84924956440
dc.identifier.scopusqualityQ3
dc.identifier.startpage611
dc.identifier.urihttps://hdl.handle.net/11480/3967
dc.identifier.volume28
dc.identifier.wosWOS:000351657400030
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherUNIV KARACHI
dc.relation.ispartofPAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSynthetic organoselenium compounds
dc.subjectantioxidant activity
dc.subjectantimicrobial activity
dc.titleSynthesis, antioxidant and anti-microbial properties of two organoselenium compounds
dc.typeArticle

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