First synthesis of 2-[alkylamino(diethoxyphosphoryl)methyl] acrylic ethyl esters
Küçük Resim Yok
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The ethyl alpha-bromomethyl-beta-(diethoxyphosphoryl)acrylic acid ester 9 has been prepared by addition of bromine to allylphosphonate 7 then dehydrobromination with DBU in acetonitrile. Reaction of allylic bromide 9 with primary amines in a bimolecular S(N)2'-type mechanism in methanol at low temperature, gives rise to the 2-[alkylamino(diethoxyphosphoryl)methyl]acrylic acid ethyl esters 6. (C) 2002 Elsevier Science Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
dimethyl alpha-(bromomethyl)fumarate, 2-[alkylamino(diethoxyphosphoryl)methyl]acrytic acid esters
Kaynak
Tetrahedron Letters
WoS Q Değeri
Q2
Scopus Q Değeri
Q3
Cilt
44
Sayı
3
