Effect of temperature on separation of purine and pyrimidine bases on novel chelating resin
Küçük Resim Yok
Tarih
2002
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The novel chelating resin poly-bis [4-(4'-biphenyl)oxamidine]-diaminoglyoxime (PLH2) has been modified as ligand-exchange material with Co(II). The possibility of using PLH2 as ligand exchanger in the chromatographic separation of nucleic acid bases and nucleosides has been studied at various temperatures. PLH2 offers the advantage of combining high sorption capacity with high selectivity for the ligands. It has a strong driving force for ligand sorption. Ligand-exchange chromatography on Co(II)-loaded functionalized PLH2 can be a useful alternative method for separation of nucleic acid bases and nucleosides. © 2002 Elsevier Science B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Ligand-exchange chromatography, Nucleic acid bases, Nucleosides, PLH2
Kaynak
Separation and Purification Technology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
28
Sayı
1