Effect of temperature on separation of purine and pyrimidine bases on novel chelating resin

Küçük Resim Yok

Tarih

2002

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The novel chelating resin poly-bis [4-(4'-biphenyl)oxamidine]-diaminoglyoxime (PLH2) has been modified as ligand-exchange material with Co(II). The possibility of using PLH2 as ligand exchanger in the chromatographic separation of nucleic acid bases and nucleosides has been studied at various temperatures. PLH2 offers the advantage of combining high sorption capacity with high selectivity for the ligands. It has a strong driving force for ligand sorption. Ligand-exchange chromatography on Co(II)-loaded functionalized PLH2 can be a useful alternative method for separation of nucleic acid bases and nucleosides. © 2002 Elsevier Science B.V. All rights reserved.

Açıklama

Anahtar Kelimeler

Ligand-exchange chromatography, Nucleic acid bases, Nucleosides, PLH2

Kaynak

Separation and Purification Technology

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

28

Sayı

1

Künye