Immunohistochemical localization of irisin in mole rats (Spalax leucodon)

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dc.authoridGUR, FATIH MEHMET/0000-0001-7748-3272
dc.authoridTARAKCI GENCER, BERRIN/0000-0002-5931-9919
dc.contributor.authorGur, F. M.
dc.contributor.authorTimurkaan, S.
dc.contributor.authorYalcin, M. H.
dc.contributor.authorGirgin, A.
dc.contributor.authorTarakci, B. Gencer
dc.date.accessioned2024-11-07T13:32:12Z
dc.date.available2024-11-07T13:32:12Z
dc.date.issued2017
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractIrisin was first identified in skeletal muscle cells. It is an exercise protein that is secreted into the circulation; it causes conversion of white adipose tissue to brown adipose tissue. We investigated irisin immunoreactivity in mole rat (Spalax leucodon) tissues. We examined cerebellum, pituitary, heart, liver, pancreas, spleen, uterus, kidney and striated muscle in female adult mole rats. Tissues were processed, embedded in paraffin, sectioned at 5 m and stained immunohistochemically for irisin. Irisin immunostaining was detected in the cytoplasm of stained cells; the cytoplasm of Purkinje cells was unstained. We found that irisin may be synthesized in many tissues. The function of locally synthesized irisin currently is unknown.
dc.identifier.doi10.1080/10520295.2017.1303194
dc.identifier.endpage251
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue4
dc.identifier.pmid28409694
dc.identifier.scopus2-s2.0-85017459619
dc.identifier.scopusqualityQ2
dc.identifier.startpage245
dc.identifier.urihttps://doi.org/10.1080/10520295.2017.1303194
dc.identifier.urihttps://hdl.handle.net/11480/15277
dc.identifier.volume92
dc.identifier.wosWOS:000401560000001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofBiotechnic & Histochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectcerebellum
dc.subjectheart
dc.subjectimmunohistochemistry
dc.subjectirisin
dc.subjectkidney
dc.subjectliver
dc.subjectmole rats
dc.subjectpancreas
dc.subjectpituitary
dc.subjectSpalax leucodon
dc.titleImmunohistochemical localization of irisin in mole rats (Spalax leucodon)
dc.typeArticle

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