The Evaluation of Peripapillary Retinal Nerve Fiber Layer Thickness Changes in Patients with Retinitis Pigmentosa and Patients with Early-Late Stage Glaucoma

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dc.contributor.authorZor, Kursad Ramazan
dc.contributor.authorKucuk, Erkut
dc.contributor.authorBicer, Gamze Yildirim
dc.contributor.authorKivrak, Ulviye
dc.date.accessioned2024-11-07T13:31:34Z
dc.date.available2024-11-07T13:31:34Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractObjective: The aim of the study is to evaluate the peripapillary retinal nerve fiber layer (RNFL) thickness of patients with retinitis pigmentosa (RP) and patients with early- and late-stage glaucoma using spectral domain optical coherence tomography (SD-OCT), and investigate the similarity and differences of RNFL thickening and thinning regions between these groups. Methods: This cross-sectional study was carried out in Nigde Omer Halisdemir University Training and Research Hospital. The patients were divided into three groups; retinitis pigmentosa (group 1), early-stage glaucoma (group 2), and medium- and advanced-stage glaucoma (group 3). The RNFL thickness of all patients were measured. Each group consisted of 20 patients. Results: RNFL thinning was most frequently detected in the inferior quadrant, and then in the superior quadrant in all 3 groups and thickening was not detected in these 2 quadrants in glaucoma groups. The thickening was most frequently detected in the temporal quadrant, and in the 9 o' clock segment in all groups. In groups 1 and 2, the nasal quadrant was second after the temporal quadrant in RNFL thickening. RNFL thickening and thinning regions were found to be similar in these 2 diseases, which progress with ganglion cell damage. The horizontal quadrants were less affected and vertical quadrants were more affected regardless of the disease. Conclusion: The similar changes in the RNFL layer in these 2 different diseases with different mechanisms suggest that ganglion cells might have a specific response to various disease processes.
dc.identifier.doi10.12996/gmj.2022.82
dc.identifier.endpage368
dc.identifier.issn2147-2092
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85140321469
dc.identifier.scopusqualityQ4
dc.identifier.startpage365
dc.identifier.urihttps://doi.org/10.12996/gmj.2022.82
dc.identifier.urihttps://hdl.handle.net/11480/14928
dc.identifier.volume33
dc.identifier.wosWOS:000863207700010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGazi Univ, Fac Med
dc.relation.ispartofGazi Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectglaucoma
dc.subjectperipapillary retinal nerve fiber layer
dc.subjectretinitis pigmentosa
dc.subjectspectral domain optical coherence tomography
dc.titleThe Evaluation of Peripapillary Retinal Nerve Fiber Layer Thickness Changes in Patients with Retinitis Pigmentosa and Patients with Early-Late Stage Glaucoma
dc.title.alternativeRetinitis Pigmentosa ve Erken-Geç Evre Glokom Hastalarinda Peripapiller Retinal Sinir Lifi Tabakasi Kalinli?i De?işimlerinin De?erlendirilmesi
dc.typeArticle

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