Role of orthopedia homebox protein in subclassification of pulmonary carcinoid tumors: Retrospective analysis of 110 cases

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dc.authoridfindik, gokturk/0000-0002-8861-7608
dc.contributor.authorCetin, Mehmet
dc.contributor.authorFindik, Gokturk
dc.contributor.authorDemirag, Funda
dc.contributor.authorTurk, Ilteris
dc.contributor.authorAydogdu, Koray
dc.date.accessioned2024-11-07T13:32:02Z
dc.date.available2024-11-07T13:32:02Z
dc.date.issued2023
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractBackground: Orthopedia homeobox protein (OTP), highlighted as a sensitive and specific marker for pulmonary carcinoids, may provide a more objective criterion for subclassification. Materials and Methods: A total of 110 patients who underwent surgery for pulmonary carcinoids (2009-2019) were included. Gender, age, application complaint, tumor diameter and location, typical and atypical tumor type, lymph node involvement, stage, recurrence, and survival data were evaluated retrospectively with OTP nuclear staining. Results: The sensitivity of OTP was 66.4%. OTP in subclassifying pulmonary carcinoids was not significant. There was no significant relationship between OTP and lymph node involvement, recurrence, and survival. Conclusion: OTP does not provide significant results in the subclassification of typical and atypical carcinoid tumors and the evaluation of recurrence and survival of carcinoid tumor cases.
dc.identifier.doi10.4103/ijpm.ijpm_210_22
dc.identifier.endpage789
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.issue4
dc.identifier.pmid38084533
dc.identifier.scopus2-s2.0-85179638564
dc.identifier.scopusqualityQ3
dc.identifier.startpage786
dc.identifier.urihttps://doi.org/10.4103/ijpm.ijpm_210_22
dc.identifier.urihttps://hdl.handle.net/11480/15181
dc.identifier.volume66
dc.identifier.wosWOS:001146777400015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofIndian Journal of Pathology and Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241106
dc.subjectAtypical
dc.subjectclassification
dc.subjectorthopedia homebox protein
dc.subjectpulmonary carcinoid
dc.subjecttypical
dc.titleRole of orthopedia homebox protein in subclassification of pulmonary carcinoid tumors: Retrospective analysis of 110 cases
dc.typeArticle

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