Antioxidative role of selenium on some tissues of (Cd2+, Cr3+)-induced rainbow trout

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dc.contributor.authorOrun, Ibrahim
dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorOzdemir, IlKnur
dc.contributor.authorAlkan, Aysel
dc.contributor.authorErdogan, Kenan
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2008
dc.departmentNiğde ÖHÜ
dc.description.abstractChemical toxic pollutants (especially heavy metals) are important sources of reactive oxygen species (ROS) in biological systems. Membrane phospholipids of aerobic organisms are continually subjected to oxidant challenges from endogenous and exogenous sources, while peroxidized membranes and lipid peroxidation products represent constant threats to aerobic cells. The primary antioxidant protection against free radical and ROS is provided by the enzymes glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) and catalase (CAT), respectively. The trace element selenium has been implicated in chemo-prevention and drug-resistance through reduction of oxidative stress. Selenium could prevent damage to the unsaturated fatty acid Of subcellular membranes by lipid peroxidation induced by free radicals. The results reported here show that sodium selenite has an important contribution to antioxidative defense for the spleen and heart of rainbow trout. The ability of sodium selenite to prevent the oxidative stress induced by heavy metals (Cd2+, Cr3+) in fish was rationalized. (C) 2007 Elsevier Inc. All rights reserved.
dc.description.sponsorshipInonu University Research Fund [BAP 2004/27]
dc.description.sponsorshipThis work was supported by Inonu University Research Fund (BAP 2004/27).
dc.identifier.doi10.1016/j.ecoenv.2007.07.008
dc.identifier.endpage75
dc.identifier.issn0147-6513
dc.identifier.issn1090-2414
dc.identifier.issue1
dc.identifier.pmid17920681
dc.identifier.scopus2-s2.0-48049085257
dc.identifier.scopusqualityQ1
dc.identifier.startpage71
dc.identifier.urihttps://dx.doi.org/10.1016/j.ecoenv.2007.07.008
dc.identifier.urihttps://hdl.handle.net/11480/5201
dc.identifier.volume71
dc.identifier.wosWOS:000258550400009
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherACADEMIC PRESS INC ELSEVIER SCIENCE
dc.relation.ispartofECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectantioxidant enzyme
dc.subjectheavy metals
dc.subjectlipid peroxidation
dc.subjectOncorhynchus mykiss
dc.subjectoxidative stress
dc.subjectselenium
dc.subjectspleen
dc.subjectheart
dc.titleAntioxidative role of selenium on some tissues of (Cd2+, Cr3+)-induced rainbow trout
dc.typeArticle

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