Lepiota castanea mushroom growing in Turkiye does not contain phallotoxins and amatoxins

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dc.authoridHoroz, Ersan/0000-0003-1376-9401
dc.authoridYilmaz, Ismail/0000-0002-4474-9617
dc.contributor.authorYilmaz, Ismail
dc.contributor.authorAkata, Ilgaz
dc.contributor.authorHoroz, Ersan
dc.contributor.authorKaya, Ertugrul
dc.date.accessioned2024-11-07T13:34:15Z
dc.date.available2024-11-07T13:34:15Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractThe number of poisoning cases caused by the Lepiota genus is globally increasing. This genus has more poisonous species than the Amanita genus, and many Lepiota species can cause severe toxicity and death if ingested. As recognized in the literature, L. castanea is a toxic species containing amatoxin. Although crude analytical methods have shown that L. castanea contains amatoxins, more recent and sensitive analyses suggest otherwise. Toxin concentrations can vary even among the same fungal species due to geographical and climatic differences. Therefore, this confusion can be resolved by analyzing L. castanea toxins from different geographical regions. This study aimed to demonstrate the toxin levels of L. castanea collected from forests in different regions of Turkiye (Istanbul and Kocaeli) using sensitive methods. The collected mushrooms were analyzed for alpha amanitin, beta amanitin, gamma amanitin, amanin, phallacidin, and phalloidin levels using RP-HPLC-UV and LCESI-MS/MS methods. L. castanea mushroom was found to be free of amatoxin and phallotoxin. Our study revealed for the first time that L. castanea mushrooms from different geographical regions of Turkiye do not contain amatoxin and phallotoxin. Supporting these findings with new studies from different parts of the world would be appropriate.
dc.description.sponsorshipAnkara University Research Fund Proj- ect [15H0430001]
dc.description.sponsorshipThis project is supported by Ankara University Research Fund Proj- ect Number: 15H0430001. The icons used in the graphical abstract were taken from www.flaticon.com , which can be subscribed to free of charge.
dc.identifier.doi10.1016/j.toxicon.2024.107736
dc.identifier.issn0041-0101
dc.identifier.issn1879-3150
dc.identifier.pmid38670498
dc.identifier.scopus2-s2.0-85191201808
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1016/j.toxicon.2024.107736
dc.identifier.urihttps://hdl.handle.net/11480/15873
dc.identifier.volume243
dc.identifier.wosWOS:001235892100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofToxicon
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectAmanitins
dc.subjectPhallotoxins
dc.subjectLepiota castanea
dc.subjectChromatography
dc.subjectHigh Pressure liquid
dc.subjectTandem mass spectrometry
dc.titleLepiota castanea mushroom growing in Turkiye does not contain phallotoxins and amatoxins
dc.typeArticle

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