Investigation of Morphometric Characteristics of the Mesencephalon in a Healthy Turkish Population: An MRI-Based Morphometric Study
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springernature
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: Due to the important functions of the mesencephalon, knowledge of its morphometric characteristics in a healthy population is important for any pathological diagnosis. The aim of this study was to determine the specific morphometric values of the mesencephalon in a healthy Turkish population.Methods: Magnetic resonance (MR) images of 184 subjects (98 females, 86 males) with a mean age of 47.33 years (range 18 to 85 years) were included in the study. Then, parameter measurements were performed on 1.5 T MR images, and MicroDicom Digital Imaging and Communications in Medicine (DICOM) viewer 2022.1 (MicroDicom Ltd., Sofia, Bulgaria) software program was used for the measurements.Results: The mean sagittal diameter of the right cerebral peduncle was 17.17 +/- 2.03 mm, the mean crosssectional area of the right cerebral peduncle was 171.75 +/- 32.81 mm(2), the mean transverse diameter of the left cerebral peduncle was 16.60 +/- 2.32 mm, sagittal diameter of tectum and tegmentum 17.01 +/- 1.57 mm, the cross-sectional area of tectum and tegmentum 223.40 +/- 27.37 mm(2) and pontomesencephalic angle 52.03(degrees)+/- 10.61(degrees), while in males these values were 18.26 +/- 2.38 mm, 182.61 +/- 38.57 mm(2), 17.39 +/- 2.57 mm, 17.76 +/- 1.90 mm, 237.20 +/- 35.94 mm(2) and 56.77(degrees)+/- 9.78(degrees), respectively. Except for the mamillopontine distance, there was a statistically significant difference between genders in the other parameters (p<0.05).Conclusion: In conclusion, the findings related to the mesencephalon obtained in this study are presented for the first time in a healthy Turkish population. Especially, the cerebral peduncle cross-sectional area, tectum and tegmentum cross-sectional area, and cerebral peduncle transverse diameter can be evaluated clinically. We believe that knowledge of these values will guide specialists and radiologists in the diagnosis of any pathologic condition. Furthermore, the pontomesencephalic angle and mamillopontine distance have been identified as potentially useful landmarks in the diagnosis of intracranial hypotension and hydrocephalus. In particular, these angles can be measured in patient groups and may be a potential landmark in making an alternative diagnosis.
Açıklama
Anahtar Kelimeler
pontomesencephalic angle, turkish population, magnetic resonance imaging, mesencephalon morphometry, age and sex differences
Kaynak
Cureus Journal of Medical Science
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
15
Sayı
11
