Dietary polyphenols as therapeutic agents to combat COVID-19

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dc.contributor.authorSarfraz, Iqra
dc.contributor.authorRasul, Azhar
dc.contributor.authorAdem, Şevki
dc.contributor.authorUcak, Ilknur
dc.contributor.authorSarfraz, Ayesha
dc.contributor.authorBukhari, Shazia Anwer
dc.contributor.authorElfiky, Abdo A.
dc.date.accessioned2024-11-07T10:40:27Z
dc.date.available2024-11-07T10:40:27Z
dc.date.issued2022
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractThe emerging outbreak of COVID-19 infection posed serious threat to human lives, claiming thousands of deaths worldwide. Both the emergence and subsequent transmission of SARS-CoV-2 underscore the urgent and critical need for the identification and development of effective preventive and therapeutic agents against COVID-19. This chapter aims to focus on promising anti-COVID-19 dietary polyphenols such as hesperidin, naringenin, Epigallocatechin gallate, and curcumin, their mechanism of action, safe dosage, toxicity, and bioavailability for future public health practices and research. Based on various computational, in vitro and in vivo pieces of evidence supporting efficacy, safety, and good bioavailability of polyphenols, this chapter demonstrates the potential of these entities for the prevention and development of therapeutics for the management of COVID-19. Although dietary polyphenols have been systematically studied from pharmacological point of view, a vast field of pr-clinical and clinical exploration still appears to be open for the research to fully validate their potential for the treatment of viral infections. © 2022 Elsevier Inc. All rights reserved.
dc.identifier.doi10.1016/B978-0-323-95578-2.00016-9
dc.identifier.endpage215
dc.identifier.isbn978-032395578-2978-032395579-9
dc.identifier.scopus2-s2.0-85142850216
dc.identifier.scopusqualityN/A
dc.identifier.startpage203
dc.identifier.urihttps://doi.org/10.1016/B978-0-323-95578-2.00016-9
dc.identifier.urihttps://hdl.handle.net/11480/11685
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofCoronavirus Drug Discovery: Druggable Targets and In Silico Update: Volume 3
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectCOVID-19
dc.subjectDietary polyphenols
dc.subjectNatural products
dc.subjectSARS-CoV-2 M<sup>pro</sup>
dc.subjectViral infection
dc.titleDietary polyphenols as therapeutic agents to combat COVID-19
dc.typeBook Chapter

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