The effect of adrenaline and trypan blue used during cataract surgery on anatomical and functional outcomes in pseudoexfoliation syndrome patients

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dc.authoridOzer, Omer/0000-0003-0329-0931
dc.contributor.authorOzer, Omer
dc.contributor.authorDogan, Levent
dc.contributor.authorBaysal, Zeki
dc.date.accessioned2024-11-07T13:24:16Z
dc.date.available2024-11-07T13:24:16Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractPurposeTo evaluate the effect of the intracameral adrenaline and trypan blue used during cataract surgery on corneal endothelial parameters in pseudoexfoliation syndrome (PEX) patients.MethodsThe patients were divided into four groups according to intraoperative use of agents during cataract surgery: intracameral adrenaline (1/10,000, 0.1 ml) (group 1), trypan blue (0.6 mg/ml, 0.1 ml) (group 2), combination of adrenaline and trypan blue (group 3) and none (group 4).ResultsPreoperative ECD, CV, HEX and CCT parameters were similar between the groups. A mean loss of 12.7% in ECD was observed at the postoperative third months compared to the preoperative. In group 3, ECD was found to be lower in the postoperative third months compared to the preoperative (p = 0.014). In the other groups, no statistically significant difference was found in preoperative and postoperative comparisons.ConclusionIn conclusion, the utilization of intracameral adrenaline or trypan blue did not cause a significant difference in corneal endothelium in PEX patients. However, their combined use may have a negative effect on endothelial cell density. In a cataract surgery performed in the presence of PEX, the increased likelihood of endothelial damage should be taken into consideration, and appropriate precautions should be taken preoperatively and intraoperatively.
dc.identifier.doi10.1080/15569527.2024.2402405
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.pmid39250681
dc.identifier.scopus2-s2.0-85204028306
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1080/15569527.2024.2402405
dc.identifier.urihttps://hdl.handle.net/11480/14022
dc.identifier.wosWOS:001311910300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofCutaneous and Ocular Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectAdrenaline
dc.subjectcataract
dc.subjectendothelial cell density
dc.subjectpseudoexfoliation
dc.subjectspecular
dc.subjecttrypan blue
dc.titleThe effect of adrenaline and trypan blue used during cataract surgery on anatomical and functional outcomes in pseudoexfoliation syndrome patients
dc.typeArticle

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