The importance of coordination in preventing overdiagnosis: a retrospective analysis of unabsorbed oxidized regenerated cellulose

Basit Öğe Kaydı
dc.authoridTurk, Ilteris/0000-0001-6385-4722
dc.authoridfindik, gokturk/0000-0002-8861-7608
dc.authoridSolak, Necati/0000-0003-1046-5410
dc.authoridOzturk, Ayperi/0000-0003-0692-4784
dc.authoridbabacan, fatma/0009-0001-1041-9919
dc.contributor.authorTurk, Ilteris
dc.contributor.authorCetin, Mehmet
dc.contributor.authorBabacan, Fatma
dc.contributor.authorSolak, Necati
dc.contributor.authorAgackiran, Yetkin
dc.contributor.authorOzturk, Ayperi
dc.contributor.authorAcar, Leyla Nesrin
dc.date.accessioned2024-11-07T13:32:57Z
dc.date.available2024-11-07T13:32:57Z
dc.date.issued2024
dc.departmentNiğde Ömer Halisdemir Üniversitesi
dc.description.abstractBackgroundOxidized regenerated cellulose (ORC) is commonly used to control small intraoperative bleedings in lung cancer surgery. However, difficulties in its absorption may lead to complications that can mimic malignancy recurrence in the affected areas, and may require further examination.MethodsBetween 2015 and 2022, patients who underwent malignant tumour resection and lymph node dissection and were subsequently evaluated for suspected lymph node recurrence and underwent EBUS-guided needle biopsy were included in the study. Pathology reports of these patients showed an ORC-related foreign body type granulomatous reaction. Such reactions, caused by delayed absorption of ORC, can mimic malignancy recurrence and result in unnecessary biopsies.ResultsIn a total of 13 patients (10 males), pathology was observed in 18 lymph node areas after malignant resection and lymph node dissection, and ORC was detected in subcarinal and inferior paratracheal lymph node areas in all patients. The average age of the patients was calculated as 63.1 years (range 51-74). The mean SUVmax value observed in these lymph node areas on PET/CT was 5.22 (range 0-14.36). Although the SUVmax value decreased as the time between surgery and EBUS increased, no statistically significant difference was observed (p = 0.100).ConclusionThe study suggests that in cases of suspected unexpected lymph node recurrence in postoperative follow-up of lung cancer, it is important for clinicians to communicate with the surgeon and re-evaluate the use of ORC by reviewing the operative notes. This may help in determining an appropriate further investigation strategy.
dc.identifier.doi10.1007/s13304-023-01624-2
dc.identifier.endpage303
dc.identifier.issn2038-131X
dc.identifier.issn2038-3312
dc.identifier.issue1
dc.identifier.pmid37558972
dc.identifier.scopus2-s2.0-85167452124
dc.identifier.scopusqualityQ2
dc.identifier.startpage299
dc.identifier.urihttps://doi.org/10.1007/s13304-023-01624-2
dc.identifier.urihttps://hdl.handle.net/11480/15701
dc.identifier.volume76
dc.identifier.wosWOS:001045107500003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer-Verlag Italia Srl
dc.relation.ispartofUpdates in Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241106
dc.subjectEndobronchial ultrasonography
dc.subjectOxidized regenerated cellulose
dc.subjectPET
dc.subjectCT
dc.titleThe importance of coordination in preventing overdiagnosis: a retrospective analysis of unabsorbed oxidized regenerated cellulose
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu