Corneal epithelial damage and impaired tear functions in patients with inflamed pinguecula

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dc.contributor.authorKüçük E.
dc.contributor.authorYilmaz U.
dc.contributor.authorZor K.R.
dc.date.accessioned2019-08-01T13:38:39Z
dc.date.available2019-08-01T13:38:39Z
dc.date.issued2018
dc.departmentNiğde ÖHÜ
dc.description.abstractPurpose. In this study, we evaluated corneal epithelial integrity and tear film parameters in patients with inflamed pinguecula and compared these findings with their fellow eyes and with healthy controls. Methods. We evaluated the fluorescein staining properties and performed the tear break-up time (TBUT) test and Schirmer 2 test (ST2) measurements of 32 patients who had symptomatic unilateral inflamed pinguecula and compared the results with their fellow eyes and also with an age- and sex-matched control group. Results. Twenty-three eyes (72%) in the inflamed pinguecula group and 1 eye (3.1%) in the fellow eyes group had punctate epithelial staining (PES) or epithelial defect on the nasal cornea (p < 0.001).There was no PES or epithelial defect in the control group. Eyes with inflamed pinguecula (n = 32) had lower TBUT and ST2 values compared to the control group (n = 32) (p < 0.001 for both). Fellow eyes (n = 32) also had lower TBUT and ST2 values compared to the control group (p =0.003 for both).There was no difference in the TBUT and ST2 results between the eyes with inflamed pinguecula and fellow eyes (p =0.286 and p = 0.951, respectively). Conclusion. A high percentage of eyes with inflamed pinguecula had nasal corneal epithelial staining or epithelial defect. We also found lower TBUT and ST2 results in eyes with inflamed pinguecula and the fellow eyes compared to the control group.These findings may be important in pathogenesis of pinguecula and pterygium and also in uncovering their relation. © 2018 ErkutKüçük et al.
dc.identifier.doi10.1155/2018/2474173
dc.identifier.issn2090004X
dc.identifier.pmid30515317
dc.identifier.scopus2-s2.0-85062767610
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://dx.doi.org/10.1155/2018/2474173
dc.identifier.urihttps://hdl.handle.net/11480/1721
dc.identifier.volume2018
dc.identifier.wosWOS:000449876100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[0-Belirlenecek]
dc.language.isoen
dc.publisherHindawi Limited
dc.relation.ispartofJournal of Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleCorneal epithelial damage and impaired tear functions in patients with inflamed pinguecula
dc.typeArticle

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